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Mercurochrome allergy. Immediate and delayed hypersensitivity
Abstract
We describe eight patients suffering from Mercurochrome allergy. Patch and prick tests were carried out with the following organic and inorganic mercury compounds: thimerosal, Mercurochrome, phenylmercuric acetate, phenylmercuric nitrate, metallic mercury, and mercuric chloride, and with sodium fluorescein. Two patients had an anaphylactic reaction a few minutes after application of Mercurochrome. The prick tests with Mercurochrome were positive and they were negative with the other tested products. All patch tests were negative. In the other six patients, the clinical picture was local eczema, and the patch tests were all positive with Mercurochrome and the inorganic mercuric derivatives. Positive patch tests with thimerosal were found only in two patients, and only one had a positive patch test with salts of phenylmercury. In four patients, the prick test with Mercurochrome, negative in immediate reading, gave a late eczematous reaction.
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As far as approved drugs for internal use are concerned, mercury of any kind is strictly illegal in Germany.
“As far as 'approved' drugs for internal use are concerned, mercury of any kind is strictly illegal in Germany.$^{1}$^{7}”
From A Physician’s View on Legal Aspects of the Contemporary Medical Use of Mercury in Germany (2013) · cites this paper as [17]
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A Physician’s View on Legal Aspects of the Contemporary Medical Use of Mercury in Germany
Aschoff, J. C. (2013) · Asian Medicine · doi:10.1163/15734218-12341276 · Cited by 4
Metadata
- Authors
- Galindo, P. A., Feo, F., García, R., Gómez, E., Borja, J., & Fernández, F.
- Corresponding author
- Galindo, P. A.
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 1997-11
- Volume
- 52
- Issue
- 11
- Pages
- 1138-1141
- ISSN
- 0105-4538 (ISSN-L)
- 1398-9995
- OpenAlex
- W2073867045
- Cited by
- 19
- References
- 0
- Citations by year
- 2023: 1 · 2018: 1 · 2013: 1 · 2012: 2
- FWCI
- 3.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Allergy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
- Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
- Keywords
- mercury allergy, thimerosal, inorganic mercury compounds, anaphylaxis, immediate hypersensitivity, delayed-type hypersensitivity, patch testing, prick testing, atopic dermatitis
- MeSH terms
- Adolescent, Adult, Child, Child, Preschool, Cross Reactions, Female, Humans, Hypersensitivity, Delayed, Hypersensitivity, Immediate, Male, Merbromin, Patch Tests, Skin Tests, Thimerosal, Mercury Compounds
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