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Nasal polyposis and its impact on quality of life: comparison between the effects of medical and surgical treatments
Abstract
Background Nasal polyposis (NP) is not a life-threatening disorder but may have a great impact on the quality of life (QoL). The objective of this study: (i) to investigate the health burden incurred by NP compared with the Spanish general population using the Short Form-36 Health Survey (SF-36) questionnaire; (ii) to compare the QoL outcome after medical or surgical treatment; and (iii) to assess and compare the effect of medical and surgical treatment on nasal symptoms. Methods About 109 patients with nasal polyps were included. Fifty-three patients were randomly allocated to receive oral prednisone for 2 weeks and 56 to undergo endoscopic sinus surgery. All patients administered intranasal budesonide for 12 months. Patients were evaluated for nasal symptoms, polyp size, and QoL. Results In comparison with the Spanish general population, patients with NP had worse scores on all SF-36 domains except for physical functioning. Nonasthmatic patients with NP had better QoL than asthmatic patients with NP on role physical functioning, body pain, and vitality (P Conclusion These results suggest that NP has considerable impact on a patient's QoL and that both medical and surgical treatment led to similar effects in improving QoL.
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Endoscopic surgical treatment is beneficial in patients with chronic rhinosinusitis with nasal polyps who have severe symptoms and do not respond to appropriate medical treatment.
“In CRS with NP , endoscopic surgical treatment has been shown to be beneficial in patients with severe symptoms who do not respond to appropriate medical treatment [20,127,128,212-218] and may be more cost-effective [219,220].”
From Position Paper on Nasal Obstruction: Evaluation and Treatment (2018) · cites this paper as [216]
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Cited by
Sorted by citations
Position Paper on Nasal Obstruction: Evaluation and Treatment
SEAIC Rhinoconjunctivitis Committee & SEORL Rhinology, A., Valero, A., Navarro, A., del Cuvillo, A., Alobid, I., Benito, Jr., Colás, C., de los Santos, G., Fernández Liesa, R., García-Lliberós, A., et al. (2018) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0232 · Cited by 76
Self-citationSleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis
Craig, T. J., Ferguson, B. J., & Krouse, J. H. (2008) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2007.06.002 · Cited by 70
Alt, J. A., DeConde, A. S., Mace, J. C., Steele, T. O., Orlandi, R. R., & Smith, T. L. (2015) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2015.1673 · Cited by 53
Metadata
- Authors
- Alobid, I., Benítez, P., Bernal‐Sprekelsen, M., Roca, J., Alonso, J., Picado, C., & Mullol, J.
- Affiliations
- Hospital Clínic de Barcelona (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Institut Municipal d'Assistència Sanitària (ES)
- Corresponding author
- Mullol, J.
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 2005-02-02
- Volume
- 60
- Issue
- 4
- Pages
- 452-458
- ISSN
- 0105-4538 (ISSN-L)
- 1398-9995
- OpenAlex
- W1964815975
- Cited by
- 211
- References
- 0
- Citations by year
- 2026: 6 · 2025: 2 · 2024: 7 · 2023: 16 · 2022: 14 · 2021: 7 · 2020: 12 · 2019: 10 · 2018: 5 · 2017: 7 · 2016: 16 · 2015: 9 · 2014: 17 · 2013: 8 · 2012: 7
- FWCI
- 11.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Allergy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Keywords
- nasal polyps, quality of life, endoscopic sinus surgery, medical treatment, prednisone, SF-36, health-related quality of life, nasal symptoms, polyp size, asthma, health burden
- MeSH terms
- Asthma, Endoscopy, Female, Glucocorticoids, Humans, Male, Middle Aged, Nasal Polyps, Prednisone, Quality of Life, Surveys and Questionnaires, Tomography, X-Ray Computed, Treatment Outcome
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