The DOI matches its Crossref record.
HLA Antigens and Susceptibility to Psoriasis Vulgaris in a Non‐Caucasian Population
Abstract
Fifty‐four unrelated Japanese patients with psoriasis vulgaris were tissue typed using the Sixth International Histocompatibility Workshop antisera. Two control groups were included in this study: Thirty‐one pustulosis palmaris et plantaris and 17 seborrheic dermatitis as a disease control and 66 normal, healthy, unrelated Japanese as a reference. HLA‐A1 (P = 0.0065) from the A locus and HLA‐BW37 (P = 0.0164) from the B locus were found to occur with increased frequency in patients with psoriasis vulgaris. No significant difference in antigen frequencies in pustulosis palmaris et plantaris was found, however, HLA‐AW30 and/or AW31 and HLA‐B12 occurred with increased frequency in seborrheic dermatitits. No linkage between psoriasis and HLA was observed in eight families. Therefore our findings in Japanese do not confirm the previous observation made in Caucasians of an association between psoriasis vulgaris and HLA‐B13 or BW17.
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“Indeed, one study found elevated levels of human leukocyte antigens HLA-AW30, HLA-AW31, HLA-A32, HLA-B12 and HLA-B18 in SD [3,73,74].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [74]
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Research works printed but not linked: 29
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Cited by
Sorted by citations
Seborrheic Dermatitis and Dandruff: A Comprehensive Review
(2015) · Journal of Clinical and Investigative Dermatology · doi:10.13188/2373-1044.1000019 · Cited by 398
Metadata
- Authors
- Tsuji, K., Nose, Y., Ito, M., Ozawa, A., Matsuo, I., Niizuma, K., & Ohkido, M.
- Affiliations
- Tokai University (JP)
- Corresponding author
- Tsuji, K.
- ORCID
- Ito, M.
- Venue
- Tissue Antigens
- Publisher
- Wiley
- Published
- 1976-07
- Volume
- 8
- Issue
- 1
- Pages
- 29-33
- ISSN
- 0001-2815 (ISSN-L)
- 1399-0039
- OpenAlex
- W2012346263
- Cited by
- 16
- References
- 0
- Citations by year
- 2015: 3 · 2014: 1 · 2013: 3
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Tissue Antigens (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Health Sciences › Medicine › Rheumatology › Spondyloarthritis Studies and Treatments
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- plaque psoriasis, HLA antigens, genetic susceptibility, Japanese patients, palmoplantar pustulosis, seborrheic dermatitis, HLA-B12, HLA-B13, HLA linkage, non-Caucasian populations
- MeSH terms
- Adult, Aged, Female, Histocompatibility Antigens, Histocompatibility Testing, HLA Antigens, Humans, Japan, Keratoderma, Palmoplantar, Male, Middle Aged, Phenotype, Psoriasis, Dermatitis, Seborrheic
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