The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
General method for rapid synthesis of multicomponent peptide mixtures
Abstract
A method is suggested for the synthesis of multicomponent peptide mixtures. The method is a solid phase synthesis modified in order to give a closely equimolar mixture of peptides with predetermined sequences. The main point of modification is that before every coupling cycle the resin is divided into equal parts and each portion is coupled with a different amino acid. Then the portions are mixed and before the next coupling cycle the resin is again distributed into equal portions. The method is illustrated by the synthesis of a mixture of 27 tetrapeptides and that of 180 pentapeptides.
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Cites
Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide
Merrifield, R. B. (1963) · Journal of the American Chemical Society · doi:10.1021/ja00897a025 · Cited by 7,647
Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
Kaiser, E., Colescott, R. L., Bossinger, C. D., & Cook, P. I. (1970) · Analytical Biochemistry · doi:10.1016/0003-2697(70)90146-6 · Cited by 3,516
Houghten, R. A. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.15.5131 · Cited by 1,643
König, W., & Geiger, R. (1970) · Chemische Berichte · doi:10.1002/cber.19701030319 · Cited by 1,577
Geysen, H. M., Meloen, R. H., & Barteling, S. J. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.13.3998 · Cited by 1,475
Electrophoretic Mobilities of Peptides on Paper and their Use in the Determination of Amide Groups
OFFORD, R. E. (1966) · Nature · doi:10.1038/211591a0 · Cited by 1,006
The disulphide bonds of insulin
Ryle, A. P., Sanger, F., Smith, L. F., & Kitai, R. (1955) · Biochemical Journal · doi:10.1042/bj0600541 · Cited by 927
Beitrag zur Aminosäurebestimmung auf Papierchromatogrammen
Heilmann, J., Barrollier, J., & Watzke, E. (1958) · Hoppe-Seyler´s Zeitschrift für physiologische Chemie · doi:10.1515/bchm2.1958.309.1.219 · Cited by 375
The Synthesis of Ribonuclease A
Gutte, B., & Merrifield, R. B. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)62396-8 · Cited by 303
Microsequence analysis of peptides and proteins
Hawke, D. H., Harris, D. C. H., & Shively, J. E. (1985) · Analytical Biochemistry · doi:10.1016/0003-2697(85)90278-7 · Cited by 92
Cited by
Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696
Synthesis and Applications of Small Molecule Libraries
Thompson, L. A., & Ellman, J. A. (1996) · Chemical Reviews · doi:10.1021/cr9402081 · Cited by 1,452
Combinatorial synthesis — the design of compound libraries and their application to drug discovery
Terrett, N. K., Gardner, M., Gordon, D. W., Kobylecki, R. J., & Steele, J. (1995) · Tetrahedron · doi:10.1016/0040-4020(95)00467-m · Cited by 659
Organic Chemistry on Solid Supports
Früchtel, J. S., & Jung, G. (1996) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199600171 · Cited by 648
Diversity-oriented synthesis: Exploring the intersections between chemistry and biology
Tan, D. S. (2005) · Nature Chemical Biology · doi:10.1038/nchembio0705-74 · Cited by 605
Metadata
- Authors
- FURKA, Á., SEBESTYÉN, F., ASGEDOM, M., & DIBÓ, G.
- Venue
- International Journal of Peptide and Protein Research
- Publisher
- Wiley
- Published
- 1991-06
- Volume
- 37
- Issue
- 6
- Pages
- 487-493
- ISSN
- 0367-8377 (ISSN-L)
- OpenAlex
- W2080262597
- Cited by
- 1,155
- References
- 12
- FWCI
- 9.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- FURKA, Á., SEBESTYÉN, F., ASGEDOM, M., & DIBÓ, G. (1991). General method for rapid synthesis of multicomponent peptide mixtures. International Journal of Peptide and Protein Research. https://doi.org/10.1111/j.1399-3011.1991.tb00765.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
