The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenker's) diverticulum
Abstract
Recent manometric and radiological studies suggest that the upper oesophageal sphincter has poor compliance in patients with a pharyngeal (Zenker's) diverticulum. To test the hypothesis that this phenomenon is related to structural changes within the cricopharyngeus muscle we examined, histologically, muscle strips from 14 patients with a Zenker's diverticulum and compared them with control tissue obtained at autopsy from 10 non‐dysphagic individuals. The cricopharyngeus muscle from patients and controls differed from inferior constrictor muscle by virtue of type 1 fibre predominance and greater fibre size variability. Ragged red fibres and nemaline bodies are a normal finding in the cricopharyngeus. Marked differences were observed in the cricopharyngeus muscle of Zenker's patients which demonstrated fibro‐adipose tissue replacement and fibre degeneration. It is concluded that these structural changes may account for the observed diminished upper oesophageal sphincter opening and dysphagia in patients with Zenker's diverticulum.
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Citations
Cites
Pharyngeal (Zenker's) diverticulum is a disorder of upper esophageal sphincter opening
Cook, I. J., Gabb, M., Panagopoulos, V., Jamieson, G. G., Dodds, W. J., Dent, J., & Shearman, D. J. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91508-2 · Cited by 342
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Pharyngeal (Zenker's) diverticulum is a disorder of upper esophageal sphincter opening
Cook, I. J., Gabb, M., Panagopoulos, V., Jamieson, G. G., Dodds, W. J., Dent, J., & Shearman, D. J. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91508-2 · Cited by 342
Self-citationA Method to Objectively Assess Swallow Function in Adults With Suspected Aspiration
Omari, T. I., Dejaeger, E., van Beckevoort, D., Goeleven, A., Davidson, G. P., Dent, J., Tack, J., & Rommel, N. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.051 · Cited by 142
The upper oesophageal sphincter
Singh, S., & Hamdy, S. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00662.x · Cited by 80
Metadata
- Authors
- COOK, I. J., BLUMBERGS, P., CASH, K., JAMIESON, G. G., & SHEARMAN, D. J.
- Venue
- Journal of Gastroenterology and Hepatology
- Publisher
- Wiley
- Published
- 1992-12
- Volume
- 7
- Issue
- 6
- Pages
- 556-562
- ISSN
- 0815-9319 (ISSN-L)
- 1440-1746
- OpenAlex
- W2157803408
- Cited by
- 173
- References
- 1
- FWCI
- 13.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenker's) diverticulum. https://app.cochat.ai/papers/10.1111/j.1440-1746.1992.tb01485.x
- The paper
- COOK, I. J., BLUMBERGS, P., CASH, K., JAMIESON, G. G., & SHEARMAN, D. J. (1992). Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenker's) diverticulum. Journal of Gastroenterology and Hepatology. https://doi.org/10.1111/j.1440-1746.1992.tb01485.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
