The DOI matches its Crossref record.
DOES COLCHICINE WORK? THE RESULTS OF THE FIRST CONTROLLED STUDY IN ACUTE GOUT
Abstract
Abstract We have performed the first controlled study of colchicine in acute gout, to determine its efficacy and toxicity, and to define the natural history of acute gout. Two‐thirds of colchicine‐treated patients improved after 48 hours, but only one‐third of the patients receiving placebo demonstrated similar improvement. The colchicine‐treated patients responded earlier; significant differences from placebo were shown after 18–30 hours. All patients given colchicine developed diarrhea after a median time of 24 hours (mean dose of colchicine 6.7 mg). This side effect occurred before relief of pain in most patients.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Khanna, D., Fitzgerald, J. D., Khanna, P. P., Bae, S., Singh, M. K., Neogi, T., Pillinger, M. H., Merill, J., Lee, S., Prakash, S., et al. (2012) · Arthritis Care & Research · doi:10.1002/acr.21772 · Cited by 1,536
Management of Gout in the Older Adult
Fravel, M. A., & Ernst, M. E. (2011) · The American Journal of Geriatric Pharmacotherapy · doi:10.1016/j.amjopharm.2011.07.004 · Cited by 37
Richter, A., Truthmann, J., Hummers, E., Pereira, J. F. M., Gágyor, I., Schuster, F., Witte, A., Böhm, S., Greser, A., Kamin, P., et al. (2024) · Trials · doi:10.1186/s13063-024-08066-0 · Cited by 1
Metadata
- Authors
- AHERN, M. J., REID, C., GORDON, T. P., McCREDlE, M., BROOKS, P. M., & JONES, M.
- Venue
- Australian and New Zealand Journal of Medicine
- Publisher
- Wiley
- Published
- 1987-06
- Volume
- 17
- Issue
- 3
- Pages
- 301-304
- ISSN
- 0004-8291 (ISSN-L)
- OpenAlex
- W2044504338
- Cited by
- 284
- References
- 0
- FWCI
- 1.05
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: DOES COLCHICINE WORK? THE RESULTS OF THE FIRST CONTROLLED STUDY IN ACUTE GOUT. https://app.cochat.ai/papers/10.1111/j.1445-5994.1987.tb01232.x
- The paper
- AHERN, M. J., REID, C., GORDON, T. P., McCREDlE, M., BROOKS, P. M., & JONES, M. (1987). DOES COLCHICINE WORK? THE RESULTS OF THE FIRST CONTROLLED STUDY IN ACUTE GOUT. Australian and New Zealand Journal of Medicine. https://doi.org/10.1111/j.1445-5994.1987.tb01232.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
