Blockade of NMDA receptors in the dorsomedial striatum prevents action–outcome learning in instrumental conditioning

Yin, Henry H.; Knowlton, Barbara J.; Balleine, Bernard W.

doi:10.1111/j.1460-9568.2005.04219.x

Blockade of NMDA receptors in the dorsomedial striatum prevents action–outcome learning in instrumental conditioning

Although there is consensus that instrumental conditioning depends on the encoding of action–outcome associations, it is not known where this learning process is localized in the brain. Recent research suggests that the posterior dorsomedial striatum (pDMS) may be the critical locus of these asso…