Triple oral fixed‐dose diabetes polypill versus insulin plus metformin efficacy demonstration study in the treatment of advanced type 2 diabetes (TrIED study‐II)

Bell, D. S. H.; Dharmalingam, M.; Kumar, S.; Sawakhande, R. B.

doi:10.1111/j.1463-1326.2011.01408.x

Triple oral fixed‐dose diabetes polypill versus insulin plus metformin efficacy demonstration study in the treatment of advanced type 2 diabetes (TrIED study‐II)

Aim: To compare the efficacy of a fixed‐dose triple oral diabetes polypill containing 1 or 2 mg glimepiride, 500 mg sustained‐release metformin, and 15 mg pioglitazone (GMP) administered once daily with human insulin 70/30 mix and 500 mg sustained‐release metformin administered twice daily (IM) i…