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Temporal patterns in overweight and obesity in Type 1 diabetes
Open accessAbstract
Diabet. Med. 27, 398–404 (2010) Aims Time trends in overweight and obesity in the general population have been well documented; however, temporal patterns in Type 1 diabetes (T1DM) have not been thoroughly investigated. We therefore assessed temporal patterns in overweight and obesity and predictors of weight change in 589 individuals from the Pittsburgh Epidemiology of Diabetes Complications Study, a cohort of childhood‐onset T1DM. Methods Participants were first seen in 1986–1988, when mean age and diabetes duration were 29 and 20 years, respectively, and biennially thereafter for 18 years. Overweight was defined as 25.0 ≤ body mass index (BMI) < 30.0 kg/m 2. Obesity was defined as BMI ≥ 30.0 kg/m 2. Results At baseline, the prevalence of overweight and obesity were 28.6% and 3.4%, respectively. After 18 years’ follow‐up, the prevalence of overweight increased by 47% while the prevalence of obesity increased sevenfold. Seven per cent were on intensive insulin therapy (≥ 3 insulin injections per day or on insulin pump) at baseline; by 2004–2007, this was 82%. Predictors of weight change were a higher baseline HbA 1c, symptomatic autonomic neuropathy (inversely), overt nephropathy (inversely), and going onto intensive insulin therapy during follow‐up. Conclusions These data demonstrate dramatic weight gain in T1DM and underscore the complexity of weight change in this disease.
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“Currently, over 50% of people with type 1 diabetes have overweight or obesity (180 -182).”
From Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report (2019) · cites this paper as [181]
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“Currently, over 50% of people with type 1 diabetes have overweight or obesity (180 -182).”
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“Obesity prevalence among people with type 1 diabetes has been signi fi cantly increasing (180 -182).”
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Metadata
- Authors
- Conway, B., Miller, R. G., Costacou, T., Fried, L., Kelsey, S., Evans, R. W., & Orchard, T. J.
- Affiliations
- University of Pittsburgh (US)
- VA Pittsburgh Healthcare System (US)
- Corresponding author
- Orchard, T. J.
- Venue
- Diabetic Medicine
- Publisher
- Wiley
- Published
- 2010-04
- Volume
- 27
- Issue
- 4
- Pages
- 398-404
- ISSN
- 0742-3071 (ISSN-L)
- 1464-5491
- PMC
- PMC3129711
- OpenAlex
- W2163890335
- Cited by
- 326
- References
- 24
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 24 · 2023: 20 · 2022: 25 · 2021: 24 · 2020: 22 · 2019: 24 · 2018: 33 · 2017: 25 · 2016: 26 · 2015: 19 · 2014: 17 · 2013: 16 · 2012: 12
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Diabetic Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- American Diabetes Association
- National Institutes of Health
- National Institute of Diabetes and Digestive and Kidney Diseases (R37DK034818, R01DK034818, DK-34818)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 1 diabetes, childhood-onset diabetes, overweight, obesity, weight gain, temporal trends, intensive insulin therapy, HbA1c, autonomic neuropathy, diabetic nephropathy, Pittsburgh Epidemiology of Diabetes Complications Study
- MeSH terms
- Adolescent, Adult, Diabetes Mellitus, Type 1, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Insulin, Middle Aged, Obesity, Predictive Value of Tests, Prospective Studies, Risk Factors, Time Factors, Weight Gain, Body Mass Index, Prevalence, Overweight, Young Adult
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