‘Simply forgot’ is the most frequently stated reason for missed doses of HAART irrespective of degree of adherence
Open accessAbstract
Objectives: Previous studies have reported that forgetfulness is the most frequently mentioned reason for missed doses among patients on highly active antiretroviral therapy (HAART). However, no previous study has compared the reasons given by highly nonadherent patients with the reasons given by patients with better adherence. The objective of this study was to examine further patients' self‐reported reasons for missing doses of HAART and to compare the reasons given by patients with lower adherence with those given by patients with higher adherence. Methods: All patients visiting the clinics participating in the Danish HIV cohort study during a 1‐year period (July 2002 to June 2003) were eligible if they had started HAART at least 6 months previously. Consenting patients completed an anonymous self‐administered questionnaire based upon the adult AIDS Clinical Trial Group adherence questionnaires. Lower adherence was defined as reporting a missed dose within the preceding 4 days. Results: We received usable questionnaires from 840 (75%) of the 1126 eligible patients. Patients with lower adherence reported the same reasons for missed doses as patients with higher adherence (Spearman's ρ=0.952, P<0.0001). In both groups of patients the three most frequently reported reasons for missed doses were ‘simply forgot’, ‘were away from home’, and ‘had a change in daily routines’. Conclusions: Patients with poorer adherence to HAART state the same reasons for missing doses as patients with better adherence, and ‘simply forgot’ is the most frequently stated reason.
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Forgetting to take medicine is one of the most common reasons for unintentional medication nonadherence.
“Forgetting to take medicines is one of the most common reasons for unintentional medication nonadherence.”
From Medication Adherence Reminder System for Virtual Home Assistants: Mixed Methods Evaluation Study (2021) · cites this paper as [9]
Cites
Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., Wu, A. W., & PATIENT CARE COMMITTEE & ADHERENCE (2000) · AIDS Care · doi:10.1080/09540120050042891 · Cited by 1,428 · see citing works
Reynolds, N. R., Testa, M. A., Marc, L. G., Chesney, M. A., Neidig, J. L., Smith, S. R., Vella, S., Robbins, G. K., & Protocol Teams of ACTG 384, A. 7. (2004) · AIDS and Behavior · doi:10.1023/b:aibe.0000030245.52406.bb · Cited by 204 · see citing works
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Kekwaletswe, C., & Morojele, N. (2014) · Patient Preference and Adherence · doi:10.2147/ppa.s55547 · Cited by 47 · see citing works
Medication Adherence Reminder System for Virtual Home Assistants: Mixed Methods Evaluation Study
Corbett, C. F., Combs, E. M., Chandarana, P. S., Stringfellow, I., Worthy, K., Nguyen, T., Wright, P. J., & O'Kane, J. M. (2021) · JMIR Formative Research · doi:10.2196/27327 · Cited by 14 · see citing works
“Among unintentional reasons for medication nonadherence, forgetting to take medicine is one of the most common reasons [8-10].”
Background
- Authors
- Barfod, T., Sørensen, H., Nielsen, H., Rodkjær, L., & Obel, N.
- Affiliations
- Aalborg University Hospital (DK)
- Aarhus University Hospital (DK)
- Odense University Hospital (DK)
- Venue
- HIV Medicine
- Publisher
- Wiley
- Published
- 2006-05-24
- Volume
- 7
- Issue
- 5
- Pages
- 285-290
- ISSN
- 1464-2662 (ISSN-L)
- 1468-1293
- OpenAlex
- W2002965541
- Cited by
- 59
- References
- 2
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 7 · 2020: 2 · 2019: 4 · 2018: 1 · 2017: 5 · 2016: 5 · 2015: 4 · 2014: 5 · 2013: 2 · 2012: 5
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- HIV Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Lægeforeningen
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Keywords
- highly active antiretroviral therapy, antiretroviral therapy adherence, missed doses, forgetfulness, HIV infection, daily routine changes
- MeSH terms
- Adolescent, Adult, Aged, Denmark, Drug Administration Schedule, Female, Humans, Male, Middle Aged, Patient Compliance, Self Disclosure, HIV-1, HIV Infections, Treatment Refusal, Anti-HIV Agents, Antiretroviral Therapy, Highly Active
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