The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Photodynamic therapy of eyelid basal cell carcinoma
Abstract
BACKGROUND: Photodynamic therapy (PDT; i.e. selective destroying of malignant cells by exposing them to red light after photosensitization) has been increasingly used for non-melanoma skin cancers. Due to excellent cosmetic and functional results, especially in difficult-to-treat areas, it may offer a comprehensive alternative to previous treatment modalities. OBJECTIVE: A series of six patient cases was used to evaluate the efficacy of PDT in the treatment of lower eyelid basal cell carcinoma (BCC). Methods Histological confirmation of BCC, a detailed demonstration of the technique with an illustrative series of cases and a review of related literature. RESULTS: Six patients with lower eyelid BCC were treated with two treatment sessions of PDT within a week. Five patients had a nodular type and one patient had a superficial type of BCC. The follow-up after treatment continued for 20-36 (mean 26.5) months. No recurrences were observed during the follow-up. All the patients were satisfied with the good results and tolerated the treatment well without any harm to the eyeball or surrounding skin. CONCLUSION: PDT, although experimental in the eyelid area because of the small amount of data and the lack of a long-term follow-up, may be considered a promising comprehensive alternative when treating BCC in the eyelid area.
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“The clinical efficiency for superficial basal cell carcinoma estimates from 50% to 100% complete responses and the effects of the therapy improve due to the implementation of fractional PDT sessions [111,112,113].”
From Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer (2011) · cites this paper as [112]
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Cites
Rhodes, L. E., de Rie, M. A., Leifsdottir, R., Yu, R. C., Bachmann, I., Goulden, V., Wong, G. A. E., Richard, M.-A., Anstey, A., & Wolf, P. (2007) · Archives of Dermatology · doi:10.1001/archderm.143.9.1131 · Cited by 275
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Sorted by citations
Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
Wachowska, M., Muchowicz, A., Firczuk, M., Gabrysiak, M., Winiarska, M., Wańczyk, M., Bojarczuk, K., & Golab, J. (2011) · Molecules · doi:10.3390/molecules16054140 · Cited by 265
Metadata
- Authors
- Kotimäki, J.
- Affiliations
- Kainuun keskussairaala (FI)
- Corresponding author
- Kotimäki, J
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2009-09
- Volume
- 23
- Issue
- 9
- Pages
- 1083-1087
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- OpenAlex
- W1970811571
- Cited by
- 31
- References
- 1
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 3 · 2020: 1 · 2019: 1 · 2018: 1 · 2016: 1 · 2015: 6 · 2014: 1 · 2013: 2 · 2012: 7
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the European Academy of Dermatology and Venereology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Nonmelanoma Skin Cancer Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Photodynamic Therapy Research Studies
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Keywords
- photodynamic therapy, basal cell carcinoma, eyelid tumors, lower eyelid, non-melanoma skin cancer, photosensitizers, nodular basal cell carcinoma, superficial basal cell carcinoma, treatment efficacy, recurrence
- MeSH terms
- Administration, Topical, Aged, Aged, 80 and over, Aminolevulinic Acid, Basal Cell Carcinoma, Carcinoma, Basal Cell, Eyelids, Female, Follow-Up Studies, Humans, Male, Middle Aged, Photochemotherapy, Skin Neoplasms, Treatment Outcome, Photosensitizing Agents
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