The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Cloudy and starry milia‐like cysts: how well do they distinguish seborrheic keratoses from malignant melanomas?
Open accessAbstract
Background Seborrheic keratoses are the most common skin lesions known to contain small white or yellow structures called milia‐like cysts (MLCs). Varied appearances can sometimes make it difficult to differentiate benign lesions from malignant lesions such as melanoma, the deadliest form of skin cancer found in humans. Objective The purpose of this study was to determine the statistical occurrence of MLCs in benign vs. malignant lesions. Methods A medical student with 10 months experience in examining approximately 1000 dermoscopy images and a dermoscopy‐naïve observer analysed contact non‐polarized dermoscopy images of 221 malignant melanomas and 175 seborrheic keratoses for presence of MLCs. Results The observers found two different types of MLCs present: large ones described as cloudy and smaller ones described as starry. Starry MLCs were found to be prevalent in both seborrheic keratoses and melanomas. Cloudy MLCs, however, were found to have 99.1% specificity for seborrheic keratoses among this group of seborrheic keratoses and melanomas. Conclusion Cloudy MLCs can be a useful tool for differentiating between seborrheic keratoses and melanomas.
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“Dermatoscopes in the primary care setting can inform decisions for biopsy and timely referral to dermatology, improve diagnostic accuracy of pigmented lesions, and facilitate earlier detection of melanoma and basal cell carcinoma9–20.”
From Dermoscopy practice guidelines for use in telemedicine (2022) · cites this paper as [15]
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Dermoscopy of pigmented skin lesions: Results of a consensus meeting via the Internet
Argenziano, G., Soyer, H. P., Chimenti, S., Talamini, R., Corona, R., Sera, F., Binder, M., Cerroni, L., De Rosa, G., Ferrara, G., et al. (2003) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2003.281 · Cited by 1,208
Self-citationDermoscopic Evaluation of Amelanotic and Hypomelanotic Melanoma
Menzies, S. W., Kreusch, J., Byth, K., Pizzichetta, M. A., Marghoob, A., Braun, R., Malvehy, J., Puig, S., Argenziano, G., Zalaudek, I., et al. (2008) · Archives of Dermatology · doi:10.1001/archderm.144.9.1120 · Cited by 306
Self-citationMilia: A review and classification
Berk, D. R., & Bayliss, S. J. (2008) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2008.07.034 · Cited by 134
Changchien, L., Dusza, S. W., Agero, A. L. C., Korzenko, A., Braun, R. P., Sachs, D. L., Usman, M. H. U., Halpern, A. C., & Marghoob, A. A. (2007) · Archives of Dermatology · doi:10.1001/archderm.143.8.1007 · Cited by 94
Burroni, M., Nami, N., & Rubegni, P. (2009) · Skin Research and Technology · doi:10.1111/j.1600-0846.2009.00349.x · Cited by 2
Cited by
Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults
Dinnes, J., Deeks, J. J., Chuchu, N., di Ruffano, L. F., Matin, R., Thomson, D. R., Wong, K. Y., Aldridge, R. B., Abbott, R. A., Fawzy, M., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011902.pub2 · Cited by 266
Dinnes, J., Deeks, J. J., Chuchu, N., Matin, R., Wong, K. Y., Aldridge, R. B., Durack, A., Gulati, A., Chan, S. A., Johnston, L., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011901.pub2 · Cited by 128
Dermoscopy–pathology relationship in seborrheic keratosis
Minagawa, A. (2017) · The Journal of Dermatology · doi:10.1111/1346-8138.13657 · Cited by 100
Dermoscopy practice guidelines for use in telemedicine
Deda, L. C., Goldberg, R. H., Jamerson, T. A., Lee, I., & Tejasvi, T. (2022) · npj Digital Medicine · doi:10.1038/s41746-022-00587-9 · Cited by 43
Carrera, C., Segura, S., Aguilera, P., Takigami, C. M., Gomes, A. C. B., Barreiro, A., Scalvenzi, M., Longo, C., Cavicchini, S., Thomas, L., et al. (2017) · Dermatology · doi:10.1159/000486851 · Cited by 40
Metadata
- Authors
- Stricklin, S. M., Stoecker, W. V., Oliviero, M. C., Rabinovitz, H. S., & Mahajan, S. K.
- Affiliations
- Missouri University of Science and Technology (US)
- Corresponding author
- Stoecker, W.V.
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2010-11-29
- Volume
- 25
- Issue
- 10
- Pages
- 1222-1224
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- PMC
- PMC3212814
- OpenAlex
- W1510182400
- Cited by
- 33
- References
- 5
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 2 · 2018: 4 · 2017: 3 · 2015: 4 · 2013: 2 · 2012: 3
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the European Academy of Dermatology and Venereology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (R43CA153927, R44CA101639, SBIR R44 CA-101639-02A2)
- Topics
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- seborrheic keratosis, melanoma, dermoscopy, diagnostic specificity
- MeSH terms
- Diagnosis, Differential, Humans, Melanoma, Retrospective Studies, Sensitivity and Specificity, Skin, Skin Neoplasms, Observer Variation, Keratosis, Seborrheic, Cytoplasmic Structures, Dermoscopy
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- CoChat. (2026). Citation check: Cloudy and starry milia‐like cysts: how well do they distinguish seborrheic keratoses from malignant melanomas? https://app.cochat.ai/papers/10.1111/j.1468-3083.2010.03920.x
- The paper
- Stricklin, S. M., Stoecker, W. V., Oliviero, M. C., Rabinovitz, H. S., & Mahajan, S. K. (2011). Cloudy and starry milia‐like cysts: how well do they distinguish seborrheic keratoses from malignant melanomas? Journal of the European Academy of Dermatology and Venereology. https://doi.org/10.1111/j.1468-3083.2010.03920.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
