Human fascioliasis
Open accessAbstract
Fasciola hepatica, a zoonotic liver fluke, can also cause disease in humans. Common symptoms are epigastric pain, upper abdominal pain and malaise. Fever and arthralgia are common in acute fascioliasis. Eosinophilia is the predominant laboratory finding, especially in patients with the acute form of the disease. Diagnosis and treatment is not easy, as physicians rarely encounter this disease, and effective drugs are not available in many countries. Human fascioliasis may be underestimated. Patients with eosinophilia and abdominal pain should be evaluated for F. hepatica infestation by parasitological, radiological and serological tests.
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Up to the present, only 2 human fascioliasis infections were successfully treated with albendazole (1,200 mg daily for 7 days).
“Up to the present, according to available literature, only 2 human infections were successfully treated with albendazole (1,200 mg daily for 7 days) [17,259]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [259]
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Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286 · see citing works
- Authors
- Saba, R., Korkmaz, M., Inan, D., Mamikoğlu, L., Turhan, Ö., Günseren, F., Çevikol, C., & Kabaalioğlu, A.
- Affiliations
- Akdeniz University (TR)
- Ege University (TR)
- Corresponding author
- Saba, R.
- Venue
- Clinical Microbiology and Infection
- Publisher
- Elsevier BV
- Published
- 2004-05
- Volume
- 10
- Issue
- 5
- Pages
- 385-387
- ISSN
- 1198-743X (ISSN-L)
- OpenAlex
- W3191890227
- Cited by
- 91
- References
- 0
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 6 · 2019: 5 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 3 · 2014: 2 · 2013: 2 · 2012: 4
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Clinical Microbiology and Infection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Keywords
- human fascioliasis, Fasciola hepatica, eosinophilia, abdominal pain, joint pain, fever, diagnosis, treatment, serological tests, radiological imaging
- MeSH terms
- Triclabendazole, Adult, Aged, Animals, Antibodies, Helminth, Antiplatyhelmintic Agents, Benzimidazoles, Fasciola hepatica, Fascioliasis, Female, Humans, Male, Middle Aged, Praziquantel, Albendazole
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