Facilitation of currents through rat Ca 2+‐permeable AMPA receptor channels by activity‐dependent relief from polyamine block

Rozov, Andrei; Zilberter, Yuri; Wollmuth, Lonnie P.; Burnashev, Nail

doi:10.1111/j.1469-7793.1998.361bh.x

Facilitation of currents through rat Ca 2+‐permeable AMPA receptor channels by activity‐dependent relief from polyamine block

1. In outside-out patches excised from human embryonic kidney (HEK) 293 cells expressing Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptor (AMPAR) channels, currents activated by 1 ms glutamate pulses at negative membrane potentials facilitated during and following a r…