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Cited by 336Maternal and fetal healthcareBlood transfusion and managementUterine Myomas and Treatments

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Peripartum hysterectomy in the UK: management and outcomes of the associated haemorrhage

Knight, M, UKOSS·2007·BJOG: An International Journal of Obstetrics & Gynaecology
DOI 10.1111/j.1471-0528.2007.01507.x
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Abstract

Objectives To identify women undergoing peripartum hysterectomy in the UK and to describe the causes, management and outcome of the associated haemorrhage. Design A population‐based descriptive study using the UK Obstetric Surveillance System (UKOSS). Setting All 229 hospitals with consultant‐led maternity units in the UK. Population All women in the UK delivering between February 2005 and February 2006. Methods Prospective case identification through the UKOSS monthly mailing. Main outcome measures Rates with 95% CIs. Odds ratio estimates. Results Three hundred and eighteen women underwent peripartum hysterectomy. The most commonly reported causes of haemorrhage were uterine atony (53%) and morbidly adherent placenta (39%). Women were not universally managed with uterotonic therapies. Fifty women were unsuccessfully managed with B‐Lynch or other brace suture prior to hysterectomy, 28 with activated factor VII and 9 with arterial embolisation. Twenty‐one percent of women suffered damage to other structures, 20% required a further operation and 19% were reported to have additional severe morbidity. Bladder damage was more likely in women with placenta accreta (OR 3.41, 95% CI 1.55–7.48) than in women with uterine atony. There were no significant differences in outcomes between women undergoing total or subtotal hysterectomy. Two women died; case fatality 0.6% (95% CI 0–1.5%). Conclusions For each woman who dies in the UK following peripartum hysterectomy, more than 150 survive. The associated haemorrhage is managed in a variety of ways and not universally according to existing guidelines. Further investigation of the outcomes following some of the more innovative therapies for control of haemorrhage is needed.

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Research works printed but not linked: 3

  1. Confidential Enquiry into Maternal and Child Health, 2004, Why Women Die 2000‐2002
  2. Hall M, 2004, Why Women Die 2000‐2002, 86
  3. Paterson‐Brown S, 2005, Guideline No. 27

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Metadata

Authors
Knight, M., & UKOSS
Affiliations
University of Oxford (GB)
Corresponding author
Knight, M
ORCID
Knight, M
Venue
BJOG: An International Journal of Obstetrics & Gynaecology
Publisher
Wiley
Published
2007-09-18
Volume
114
Issue
11
Pages
1380-1387
ISSN
  • 0306-5456 (ISSN-L)
  • 1470-0328
  • 1471-0528
DOI
10.1111/j.1471-0528.2007.01507.x
OpenAlex
W2044391056
Cited by
336
References
17
Citations by year
2026: 8 · 2025: 6 · 2024: 8 · 2023: 8 · 2022: 18 · 2021: 13 · 2020: 11 · 2019: 25 · 2018: 16 · 2017: 15 · 2016: 21 · 2015: 26 · 2014: 20 · 2013: 22 · 2012: 21
FWCI
22.03
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
  • PubMed (publishedVersion)
Funders
Obstetric Anaesthetists' Association
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
  • Health Sciences › Medicine › Hematology › Blood transfusion and management
  • Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
Keywords
peripartum hysterectomy, postpartum hemorrhage, uterine atony, placenta accreta, placenta accreta spectrum, B-Lynch suture, arterial embolization, factor VIIa, bladder injury, hysterectomy outcomes, case fatality, obstetric monitoring
MeSH terms
Adult, Blood Transfusion, Female, United Kingdom, Postpartum Hemorrhage, Humans, Hysterectomy, Length of Stay, Placenta Diseases, Postoperative Care, Pregnancy, Prognosis, Prospective Studies, Reoperation, Risk Factors, Uterine Inertia, Odds Ratio

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