The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
NEUTRAL AMINO ACIDS IN THE BRAIN: CHANGES IN RESPONSE TO FOOD INGESTION1
Abstract
Abstract— The brain levels of each of the aromatic and branched‐chain amino acids change 2 h after fasting rats begin to consume either a carbohydrate‐fat diet or a similar diet containing 18% or 40% protein. Carbohydrate‐fat ingestion elevates the concentrations of each of the aromatic amino acids in brain, while substantially depressing those of the branched‐chain amino acids. The inclusion of protein in this diet suppresses the increases in brain aromatic amino acids and attenuates the decreases in the branched‐chain amino acids. The changes in the brain level of each neutral amino acid following the ingestion of any of these diets correlate extremely well with the effects of the diet on the serum neutral amino acid pattern, specifically on the serum concentration ratio of each neutral amino acid to the sum of the other neutral amino acids. The diet‐induced changes in the brain level of each of the amino acids also correlate surprisingly well with the calculated rate of brain influx for each amino acid.
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Citations
Cites
Felig, P. (1975) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.44.070175.004441 · Cited by 789
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Tyrosine, Phenylalanine, and Catecholamine Synthesis and Function in the Brain2
Fernstrom, J. D., & Fernstrom, M. H. (2007) · The Journal of Nutrition · doi:10.1093/jn/137.6.1539s · Cited by 755
Self-citationJames, J. H., Jeppsson, B., Ziparo, V., & Fischer, J. (1979) · The Lancet · doi:10.1016/s0140-6736(79)92119-6 · Cited by 417
Maes, M., Scharpé, S., Meltzer, H. Y., Okayli, G., Bosmans, E., D'Hondt, P., Vanden Bossche, B., & Cosyns, P. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90003-5 · Cited by 302
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Metadata
- Authors
- Fernstrom, J. D., & Faller, D. V.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 1978-06
- Volume
- 30
- Issue
- 6
- Pages
- 1531-1538
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W2057084723
- Cited by
- 423
- References
- 1
- FWCI
- 7.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: NEUTRAL AMINO ACIDS IN THE BRAIN: CHANGES IN RESPONSE TO FOOD INGESTION1. https://app.cochat.ai/papers/10.1111/j.1471-4159.1978.tb10489.x
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- Fernstrom, J. D., & Faller, D. V. (1978). NEUTRAL AMINO ACIDS IN THE BRAIN: CHANGES IN RESPONSE TO FOOD INGESTION1. Journal of Neurochemistry. https://doi.org/10.1111/j.1471-4159.1978.tb10489.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.