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Arachidonic Acid Cascade and Signal Transduction
Abstract
Since a review on this topic in this Journal appeared (Wolfe, 1982), the CNS has proved to be a major focus in eicosanoid research. Although our knowledge is limited at the moment, the research in this field is rapidly growing. In this short review, we summarize recent progress of research (1982-1989) in this field with special attention directed to eicosanoid metabolism, functions of eicosanoids in the neuroendocrine system and synaptic transmission, current information on eicosanoid receptors, and the link between eicosanoids and cerebral circulation. Knowledge of the eicosanoids has paved the way to a better understanding of intercellular signal transduction systems, including neuronal functions.
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Citations
Cited by
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Minghetti, L. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00052-x · Cited by 567
Essential fatty acids and the brain: possible health implications
Youdim, K. A., Martin, A., & Joseph, J. A. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(00)00013-7 · Cited by 517
The Blood-Brain Barrier in Neuroinflammatory Diseases
de Vries, H. E., Kuiper, J., de Boer, A. G., Van Berkel, T. J. C., & Breimer, D. D. (1997) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01320-6 · Cited by 429
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Haag, M. (2003) · The Canadian Journal of Psychiatry · doi:10.1177/070674370304800308 · Cited by 421
Metadata
- Authors
- Shimizu, T., & Wolfe, L. S.
- Venue
- Journal of Neurochemistry
- Publisher
- Wiley
- Published
- 1990-07
- Volume
- 55
- Issue
- 1
- Pages
- 1-15
- ISSN
- 0022-3042 (ISSN-L)
- 1471-4159
- OpenAlex
- W2056402816
- Cited by
- 590
- References
- 0
- FWCI
- 20.60
- Type
- journal article
- Language
- en
- Open access
- closed
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.