Acute amphetamine down‐regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D 1 and D 2 dopamine receptors

Schwendt, Marek; Gold, Stephen J.; McGinty, Jacqueline F.

doi:10.1111/j.1471-4159.2006.03669.x

Acute amphetamine down‐regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D 1 and D 2 dopamine receptors

Administration of psychostimulants modulates mRNA of several regulators of guanine nucleotide‐binding protein signaling (RGSs) proteins in the brain. In the present study, the regulation of amphetamine‐induced decrease of RGS4 expression in the rat forebrain was evaluated. RGS4 mRNA was reduced b…