The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A SENSITIVE METHOD FOR THE ASSAY OF 5‐HYDROXYTRYPTAMINE
Open accessAbstract
The movements of a strip of fundus from a rat stomach, suspended in a 5 ml. bath at 37°, are recorded by a spring‐loaded lever. The muscle is stretched for 15 to 30 sec. between contractions. 1 ng. 5‐Hydroxytryptamine (5‐HT), 10 ng. acetylcholine or 2 to 10 μg. of histamine all produce contractions, giving tracings about 4 cm. high. In the presence of hyoscine (10−7) low concentrations of 5‐HT can be assayed directly from mixtures of the three substances. Sympathomimetic amines interfere with the assay, but this can be overcome. The preparation is robust, potentially suitable for use with an automatic assay apparatus and 10 to 100 times more sensitive than the rat uterus.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The distribution of substance P and 5‐hydroxytryptamine in the central nervous system of the dog
Amin, A. H., Crawford, T. B. B., & Gaddum, J. H. (1954) · The Journal of Physiology · doi:10.1113/jphysiol.1954.sp005229 · Cited by 704
GADDUM, J. H. (1953) · British Journal of Pharmacology and Chemotherapy · doi:10.1111/j.1476-5381.1953.tb00801.x · Cited by 200
Cited by
Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs
VANE, J. R. (1971) · Nature New Biology · doi:10.1038/newbio231232a0 · Cited by 8,605
Self-citationProposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine
Bradley, P. B., Engel, G., Feniuk, W., Fozard, J. R., Humphrey, P. P. A., Middlemiss, D. N., Mylecharane, E. J., Richardson, B. P., & Saxena, P. R. (1986) · Neuropharmacology · doi:10.1016/0028-3908(86)90207-8 · Cited by 1,258
Prostaglandins: Their Disappearance from and Release into the Circulation
FERREIRA, S. H., & VANE, J. R. (1967) · Nature · doi:10.1038/216868a0 · Cited by 892
Self-citationFLOWER, R. J., & VANE, J. R. (1972) · Nature · doi:10.1038/240410a0 · Cited by 779
Self-citationEgaña, E. (1971) · Alterations of Chemical Equilibrium in the Nervous System · doi:10.1007/978-1-4615-7175-9_22 · Cited by 517
Metadata
- Authors
- VANE, J. R.
- Venue
- British Journal of Pharmacology and Chemotherapy
- Publisher
- Wiley
- Published
- 1957-09
- Volume
- 12
- Issue
- 3
- Pages
- 344-349
- ISSN
- 0366-0826 (ISSN-L)
- OpenAlex
- W3150791457
- Cited by
- 772
- References
- 2
- FWCI
- 26.24
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A SENSITIVE METHOD FOR THE ASSAY OF 5‐HYDROXYTRYPTAMINE. https://app.cochat.ai/papers/10.1111/j.1476-5381.1957.tb00146.x
- The paper
- VANE, J. R. (1957). A SENSITIVE METHOD FOR THE ASSAY OF 5‐HYDROXYTRYPTAMINE. British Journal of Pharmacology and Chemotherapy. https://doi.org/10.1111/j.1476-5381.1957.tb00146.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
