The DOI matches its Crossref record.
A new method of destroying adrenergic nerves in adult animals using guanethidine
Open accessAbstract
Summary: The structure of sympathetic neurones in the rat has been examined with histological, fluorescence histochemical and electron microscopical methods after chronic treatment for 6 weeks with guanethidine (25 or 30 mg/kg/day i.p.). Less than 2% of the nerve cell bodies in the superior cervical ganglion remained at this time and in these cells the mitochondria were badly damaged. Few fluorescent adrenergic nerve fibres were found outside the central nervous system. This situation persisted even 4 months (the longest period studied) after cessation of treatment. This procedure is proposed as a new method of producing sympathectomy. It has the advantage of being applicable to adult animals in a variety of experimental and pathological situations. It is uniquely advantageous for denervation of the male reproductive tract.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Levine, J., Dardick, S., Roizen, M., Helms, C., & Basbaum, A. (1986) · The Journal of Neuroscience · doi:10.1523/jneurosci.06-12-03423.1986 · Cited by 345
Levine, J. D., Taiwo, Y. O., Collins, S. D., & Tam, J. K. (1986) · Nature · doi:10.1038/323158a0 · Cited by 279
Autonomic Neurotransmission: 60 Years Since Sir Henry Dale
Burnstock, G. (2009) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.052808.102215 · Cited by 137
Self-citation
Metadata
- Authors
- BURNSTOCK, G., EVANS, B., GANNON, B. J., HEATH, J. W., & JAMES, V.
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 1971-10
- Volume
- 43
- Issue
- 2
- Pages
- 295-301
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- OpenAlex
- W1937717046
- Cited by
- 223
- References
- 0
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A new method of destroying adrenergic nerves in adult animals using guanethidine. https://app.cochat.ai/papers/10.1111/j.1476-5381.1971.tb08060.x
- The paper
- BURNSTOCK, G., EVANS, B., GANNON, B. J., HEATH, J. W., & JAMES, V. (1971). A new method of destroying adrenergic nerves in adult animals using guanethidine. British Journal of Pharmacology. https://doi.org/10.1111/j.1476-5381.1971.tb08060.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
