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Guide to Receptors and Channels (GRAC), 5th edition
Open accessAbstract
The Fifth Edition of the 'Guide to Receptors and Channels' is a compilation of the major pharmacological targets divided into seven sections: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside suggestions for further reading. Available alongside this publication is a portal at http://www.GuideToPharmacology.org which is produced in close association with NC-IUPHAR and allows free online access to the information presented in the Fifth Edition.
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“Functional CRF 1 receptors are essential for the activation of the endocrine response to stress [169].”
From Anxiety, depression, and the microbiome: A role for gut peptides (2018) · cites this paper as [169]
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Kanai, Y., & Hediger, M. A. (2004) · Pfl�gers Archiv European Journal of Physiology · doi:10.1007/s00424-003-1146-4 · Cited by 450
The thermo‐TRP ion channel family: properties and therapeutic implications
Vay, L., Gu, C., & McNaughton, P. A. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01601.x · Cited by 313
Guide to Receptors and Channels (GRAC), 4th edition
Alexander, S. P. H., & Peters, J. A. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00499.x · Cited by 249
Self-citationThe oligomeric state sets GABAB receptor signalling efficacy
Comps‐Agrar, L., Kniazeff, J., Nørskov-Lauritsen, L., Maurel, D., Gassmann, M., Gregor, N., Prézeau, L., Bettler, B., Durroux, T., Trinquet, E., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.143 · Cited by 103
Lan, R., Lu, Q., Fan, P., Gatley, J. S., Volkow, N. D., Fernando, S. R., Pertwee, R. G., & Makriyannis, A. (1999) · AAPS PharmSci · doi:10.1208/ps010204 · Cited by 98
X. International Union of Pharmacology recommendations for nomenclature of new receptor subtypes.
Vanhoutte, P. M., Humphrey, P. P. A., & Spedding, M. (1996) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06936-4 · Cited by 78
Goursaud, S., Focant, M. C., Berger, J. V., Nizet, Y., Maloteaux, J., & Hermans, E. (2011) · The FASEB Journal · doi:10.1096/fj.11-182337 · Cited by 14
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Metadata
- Authors
- Alexander, S., Mathie, A., & Peters, J.
- Affiliations
- University of Nottingham (GB)
- Medway School of Pharmacy (GB)
- University of Dundee (GB)
- ORCID
- Mathie, A
- Venue
- British Journal of Pharmacology
- Publisher
- Wiley
- Published
- 2011-11
- Volume
- 164
- Issue
- s1
- Pages
- S1-324
- ISSN
- 0007-1188 (ISSN-L)
- 1476-5381
- PMC
- PMC3315626
- OpenAlex
- W2069380892
- Cited by
- 1,947
- References
- 2
- Citations by year
- 2026: 4 · 2025: 13 · 2024: 12 · 2023: 14 · 2022: 23 · 2021: 19 · 2020: 20 · 2019: 35 · 2018: 27 · 2017: 36 · 2016: 47 · 2015: 59 · 2014: 71 · 2013: 191 · 2012: 279
- FWCI
- 109.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal of Pharmacology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Discovery Research Portal (University of Dundee) (submittedVersion)
- Kent Academic Repository (University of Kent) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- therapeutic target, G protein-coupled receptors, ligand-gated ion channels, ion channels, nuclear receptors, transporters, enzymes, receptor nomenclature, pharmacological tools
- MeSH terms
- Animals, Humans, Ion Channels, Receptors, Cell Surface, Receptors, Cytoplasmic and Nuclear
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