Differences in Dermoscopic Images from Nonpolarized Dermoscope and Polarized Dermoscope Influence the Diagnostic Accuracy and Confidence Level: A Pilot Study: DIFFERENCES IN POLARIZED VS NON-POLARIZED DERMOSCOPY
Open accessAbstract
Background Studies have demonstrated differences in colors and dermoscopic structures observed with polarized dermoscopes (PDs) and nonpolarized dermoscopes (NPDs). Objective The objective was to evaluate whether diagnosis and diagnostic confidence changes when viewing dermoscopic images from NPDs and PDs. Methods A total of 100 dermatologists participated in the study. Twenty-five pigmented lesions were shown in the study, consisting of 7 seborrheic keratoses (SK), 3 basal cell carcinomas, 2 atypical nevi, 5 malignant melanomas (MM), 3 dermatofibromas, 3 blue nevi, and 2 hemangiomas. Two images of each lesion (one NPD and one PD) were included. The McNemar test and paired t-test were used for the statistical analysis. Results Ninety-one participants completed the study. Significant differences in the diagnoses were observed for the SK, atypical nevus, and MM images. Seventy-five percent and 59% of the final participants correctly diagnosed SK when presented with the NPD and PD images, respectively. For MM, 23 and 34% made the correct diagnoses with the NPD and PD images, respectively. Conclusions Viewing lesions with NPD versus PD can affect the diagnosis and diagnostic confidence of physicians that are novices with dermoscopy. Further studies including physicians at different expertise levels and a larger sample of lesions are needed to further explore the differences.
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Polarized and nonpolarized dermoscopy can provide complementary information.
“However, polarized and nonpolarized dermoscopy can provide complementary information and it is generally recommended to capture at least one dermoscopic image with polarized light25,32,39,41,42.”
From Dermoscopy practice guidelines for use in telemedicine (2022) · cites this paper as [42]
Non-polarized light has higher specificity in diagnosing epidermal structures such as milia cysts, comedo-like openings in seborrheic keratoses, and blue-white veil associated with orthokeratosis.
“Non-polarized light shall be used to visualize superficial structures and has higher specificity in diagnosing epidermal structures such as milia cysts, comedo-like openings in seborrheic keratoses, and blue-white veil associated with orthokeratosis42–44.”
From Dermoscopy practice guidelines for use in telemedicine (2022) · cites this paper as [42]
Polarized light eliminates superficial glare and can be used to visualize deep structures such as vasculature and collagen, and aid in identification of some malignant neoplasms.
“Polarized light eliminates superficial glare and should be used to visualize deep structures such as vasculature and collagen, and aid in identification of some malignant neoplasms42–45.”
From Dermoscopy practice guidelines for use in telemedicine (2022) · cites this paper as [42]
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Vascularización en dermatoscopia
Martín, J. M., Bella-Navarro, R., & Jordá, E. (2012) · Actas Dermo-Sifiliográficas · doi:10.1016/j.ad.2011.11.005 · Cited by 81 · see citing works
Dermoscopy practice guidelines for use in telemedicine
Deda, L. C., Goldberg, R. H., Jamerson, T. A., Lee, I., & Tejasvi, T. (2022) · npj Digital Medicine · doi:10.1038/s41746-022-00587-9 · Cited by 43 · see citing works
- Authors
- WANG, S. Q., DUSZA, S. W., SCOPE, A., BRAUN, R. P., KOPF, A. W., & MARGHOOB, A. A.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- University Hospital Zurich (CH)
- New York University (US)
- Corresponding author
- MARGHOOB, ASHFAQ A.
- Venue
- Dermatologic Surgery
- Published
- 2008-07-14
- Volume
- 34
- Issue
- 10
- Pages
- 1389-1395
- ISSN
- 1076-0512 (ISSN-L)
- 1524-4725
- OpenAlex
- W2123519778
- Cited by
- 79
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 8 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 7 · 2017: 7 · 2016: 6 · 2015: 7 · 2014: 5 · 2013: 1 · 2012: 10
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.zora.uzh.ch
- Licence
- other-oa
- Locations
- Dermatologic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich)
- Topics
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- polarized dermoscopy, diagnostic accuracy, diagnostic confidence, pigmented skin lesions, seborrheic keratosis, melanoma, atypical nevus
- MeSH terms
- Humans, Microscopy, Polarization, Pigmentation Disorders, Pilot Projects, Skin Diseases, Skin Neoplasms, Dermoscopy
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