Treatment of superficial infantile hemangiomas of the eyelid using the 595-nm pulsed dye laser
Abstract
Background Despite the proven effectiveness of the 595-nm pulsed dye laser (PDL) in treating superficial infantile hemangiomas, many physicians are reluctant to treat such lesions involving the eyelid. OBJECTIVE To examine the safety and efficacy of the 595-nm PDL for the treatment of superficial infantile hemangiomas of the eyelid. Materials & methods Records were reviewed for patients with superficial infantile hemangiomas of the eyelid treated with 595-nm PDL. Pre- and post-treatment photographs were compared. Reviewers rated the degree of improvement of the hemangioma as excellent (76-100%), good (51-75%), moderate (26-50%), or poor (0-25%) and indicated whether the hemangioma was 100% clear. Side effects of scarring, atrophy, hyperpigmentation, and hypopigmentation were assessed. Results Twenty-two patients met the study criteria. Eight (36.4%) demonstrated complete clearance of their hemangioma, 17 (77.3%) received an improvement rating of excellent, and five (22.7%) received a rating of good. No scarring, atrophy, or hypopigmentation was noted. Two patients (9.1%) were noted to have hyperpigmentation in the treated area. Conclusion Early treatment with the 595-nm PDL can safely and effectively diminish proliferative growth and hasten resolution of superficial infantile hemangiomas of the eyelid.
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UVA1 exerts its therapeutic effects through T cell apoptosis, collagenase induction, angiogenesis, and tissue remodeling.
“UVA1 exerts its therapeutic effects through T cell apoptosis, collagenase induction, angiogenesis, tissue remodeling [97].”
From Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy (2013) · cites this paper as [97]
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Lee, C.-H., Wu, S.-B., Hong, C.-H., Yu, H.-S., & Wei, Y.-H. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14036414 · Cited by 271 · see citing works
- Authors
- Hunzeker, C. M., & Geronemus, R. G.
- Affiliations
- Laser and Skin Surgery Center of New York (US)
- Corresponding author
- Hunzeker, Christopher M.
- Geronemus, Roy G.
- ORCID
- Geronemus, Roy G.
- Venue
- Dermatologic Surgery
- Published
- 2010-05
- Volume
- 36
- Issue
- 5
- Pages
- 590-597
- ISSN
- 1076-0512 (ISSN-L)
- OpenAlex
- W2012686403
- Cited by
- 61
- References
- 0
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 6 · 2015: 7 · 2014: 7 · 2013: 7 · 2012: 6
- FWCI
- 7.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dermatologic Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Vascular Malformations and Hemangiomas
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Health Sciences › Medicine › Neurology › Vascular Malformations Diagnosis and Treatment
- Keywords
- infantile hemangioma, eyelid hemangioma, 595 nm pulsed dye laser, laser therapy, treatment efficacy, treatment safety, hyperpigmentation, hypopigmentation, scar formation, eyelid lesions
- MeSH terms
- Child, Preschool, Eyelid Neoplasms, Female, Follow-Up Studies, Hemangioma, Humans, Infant, Male, Retrospective Studies, Severity of Illness Index, Time Factors, Treatment Outcome, Low-Level Light Therapy, Lasers, Dye
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