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Sudden Death in Epilepsy: A Study of Incidence in a Young Cohort with Epilepsy and Learning Difficulty
Abstract
Summary: Sudden death, often seizure related, may occur in patients with epilepsy. Population‐based incidence is probably on the order of 1:1,000/year. The incidence is much higher in selected groups, however. We wished to establish the incidence of sudden unexpected death (SUD) in a young cohort with severe epilepsy and learning difficulties. The study cohort included 310 pupils with epilepsy enrolled at a special residential school between April 1970 and April 1993. The follow‐up period totaling 4,135 person‐years included a period of residence at the school as well as time after leaving. Age and sex standardized overall mortality ratio was 15.9 [95% confidence interval (CI) 10.6–23.0], with 20 of 28 deaths considered epilepsy related. An incidence of sudden death cases of 1:295/year was noted. All 14 sudden deaths occurred when the pupils were not under the close supervision of the school and most were unwitnessed, which has implications for prevention.
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Cited by
Priori, S. G., Blomström-Lundqvist, C., Mazzanti, A., Blom, N., Borggrefe, M., Camm, J., Elliott, P. M., Fitzsimons, D., Hatala, R., Hindricks, G., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv316 · Cited by 3,893
Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention
Devinsky, O., Hesdorffer, D. C., Thurman, D. J., Lhatoo, S., & Richerson, G. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(16)30158-2 · Cited by 721
Unifying the definitions of sudden unexpected death in epilepsy
Nashef, L., So, E. L., Ryvlin, P., & Tomson, T. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2011.03358.x · Cited by 632
Self-citationRisk factors for sudden unexpected death in epilepsy: a case control study
Nilsson, L., Farahmand, B., Persson, P.-G., Thiblin, I., & Tomson, T. (1999) · The Lancet · doi:10.1016/s0140-6736(98)05114-9 · Cited by 522
Sudden Unexpected Death in Epilepsy: Terminology and Definitions
Nashef, L. (1997) · Epilepsia · doi:10.1111/j.1528-1157.1997.tb06130.x · Cited by 485
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Metadata
- Authors
- Nashef, L., Fish, D. R., Garner, S., Sander, J. W. A. S., & Shorvon, S. D.
- Venue
- Epilepsia
- Publisher
- Wiley
- Published
- 1995-12
- Volume
- 36
- Issue
- 12
- Pages
- 1187-1194
- ISSN
- 0013-9580 (ISSN-L)
- 1528-1167
- OpenAlex
- W2032290121
- Cited by
- 305
- References
- 0
- FWCI
- 7.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Sudden Death in Epilepsy: A Study of Incidence in a Young Cohort with Epilepsy and Learning Difficulty. https://app.cochat.ai/papers/10.1111/j.1528-1157.1995.tb01061.x
- The paper
- Nashef, L., Fish, D. R., Garner, S., Sander, J. W. A. S., & Shorvon, S. D. (1995). Sudden Death in Epilepsy: A Study of Incidence in a Young Cohort with Epilepsy and Learning Difficulty. Epilepsia. https://doi.org/10.1111/j.1528-1157.1995.tb01061.x
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