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Cited by 1,113Epilepsy research and treatmentMental Health Treatment and AccessPharmacological Effects and Toxicity Studies

The DOI matches its Crossref record; 41 of the 42 references it cites were found in a registry or an index.

Psychiatric comorbidity in epilepsy: a population-based analysis

Tellez‐Zenteno, Jose F., Patten, Scott B., Jetté, Nathalie, Williams, Jeanne, Wiebe, Samuel·2007·Epilepsia
DOI 10.1111/j.1528-1167.2007.01222.x
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Abstract

PURPOSE: The estimated prevalence of mental health disorders in those with epilepsy in the general population varies owing to differences in study methods and heterogeneity of epilepsy syndromes. We assessed the population-based prevalence of various psychiatric conditions associated with epilepsy using a large Canadian national population health survey. METHODS: The Canadian Community Health Survey (CCHS 1.2) was used to explore numerous aspects of mental health in persons with epilepsy in the community compared with those without epilepsy. The CCHS includes administration of the World Mental Health Composite International Diagnostic Interview to a sample of 36,984 subjects. Age-specific prevalence of mental health conditions in epilepsy was assessed using logistic regression. RESULTS: The prevalence of epilepsy was 0.6%. Individuals with epilepsy were more likely than individuals without epilepsy to report lifetime anxiety disorders or suicidal thoughts with odds ratio of 2.4 (95% CI = 1.5-3.8) and 2.2 (1.4-3.3), respectively. In the crude analysis, the odds of lifetime major depression or panic disorder/agoraphobia were not greater in those with epilepsy than those without epilepsy, but the association with lifetime major depression became significant after adjustment for covariates. CONCLUSIONS: In the community, epilepsy is associated with an increased prevalence of mental health disorders compared with the general population. Epilepsy is also associated with a higher prevalence of suicidal ideation. Understanding the psychiatric correlates of epilepsy is important to adequately manage this patient population.

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Metadata

Authors
Tellez‐Zenteno, J. F., Patten, S. B., Jetté, N., Williams, J., & Wiebe, S.
Affiliations
University of Calgary (CA)
Corresponding author
Wiebe, Samuel
ORCID
Venue
Epilepsia
Publisher
Wiley
Published
2007-10-05
Volume
48
Issue
12
Pages
2336-2344
ISSN
  • 0013-9580 (ISSN-L)
  • 1528-1167
DOI
10.1111/j.1528-1167.2007.01222.x
OpenAlex
W2086056052
Cited by
1,113
References
42
Citations by year
2026: 36 · 2025: 45 · 2024: 71 · 2023: 56 · 2022: 65 · 2021: 88 · 2020: 83 · 2019: 81 · 2018: 64 · 2017: 66 · 2016: 70 · 2015: 68 · 2014: 71 · 2013: 50 · 2012: 60
FWCI
17.72
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Epilepsia (publishedVersion)
  • PubMed (publishedVersion)
Funders
M.S.I. Foundation
Topics
  • Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
Keywords
epilepsy, psychiatric comorbidity, mental illness, anxiety disorders, suicidal ideation, major depressive disorder, panic disorder, agoraphobia, prevalence, community-dwelling patients, Canadian Community Health Survey
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Mental Disorders, Canada, Child, Data Collection, Major Depressive Disorder, Epilepsy, Female, Health Surveys, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Suicide, Comorbidity, Prevalence, Logistic Models, Odds Ratio, Diagnosis, Dual (Psychiatry), Substance-Related Disorders

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