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International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy
Open accessAbstract
In order to address the major impact on quality of life and epilepsy management caused by associated neuropsychiatric conditions, an international consensus group of epileptologists met with the aim of developing clear evidence-based and practice-based statements to provide guidance on the management of these conditions. Using a Delphi process, this group prioritized a list of key management areas. These included: depression, anxiety, psychotic disorders, nonepileptic seizures, cognitive dysfunction, antiepileptic drug (AED)-related neurobehavioral disorders, suicidality, disorders in children and adolescents, disorders in children with intellectual disability, and epilepsy surgery. Clinical practice statements were developed for each area and consensus reached among members of the group. The assessment and management of these conditions needs to combine knowledge of psychiatric disorders, knowledge of the impact of epilepsy and its treatment on psychopathology, and an ability to deliver care within epilepsy services. The aim of these statements is to provide guidance on quality care for people with epilepsy that have a range of neuropsychiatric disorders.
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“To date it has been relatively easy for healthcare purchasers to ignore references to the provision of psychological treatments in epilepsy treatment guidelines because there is insufficient evidence for the effectiveness of such interventions [9, 10].”
From A prospective service evaluation of acceptance and commitment therapy for patients with refractory epilepsy (2015) · cites this paper as [9]
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“However, there is a lack of accessible and cost-effective psychological and behavioural interventions that are supported by high quality empirical evidence.”
From A prospective service evaluation of acceptance and commitment therapy for patients with refractory epilepsy (2015) · cites this paper as [9]
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“This is likely to be one of the reasons why this treatment need therefore remains largely unmet [9, 11].”
From A prospective service evaluation of acceptance and commitment therapy for patients with refractory epilepsy (2015) · cites this paper as [9]
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Metadata
- Authors
- Kerr, M. P., Mensah, S., Besag, F., de Toffol, B., Ettinger, A., Kanemoto, K., Kanner, A., Kemp, S., Krishnamoorthy, E., LaFrance Jr, W. C., Mula, M., Schmitz, B., van Elst, L. T., Trollor, J., & Wilson, S. J.
- Affiliations
- University of Wales (GB)
- Cardiff and Vale University Health Board (GB)
- South Essex Partnership University Foundation NHS Trust (GB)
- Long Island Jewish Medical Center (US)
- Aichi Medical University (JP)
- Rush University Medical Center (US)
- Voluntary Health Services Hospital (IN)
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- Charité – Universitätsmedizin Berlin (DE)
- UNSW Sydney (AU)
- The University of Melbourne (AU)
- Corresponding author
- Kerr, Mike P.
- ORCID
- Venue
- Epilepsia
- Publisher
- Wiley
- Published
- 2011-09-28
- Volume
- 52
- Issue
- 11
- Pages
- 2133-2138
- ISSN
- 0013-9580 (ISSN-L)
- OpenAlex
- W1536128866
- Cited by
- 425
- References
- 9
- Citations by year
- 2026: 14 · 2025: 20 · 2024: 31 · 2023: 19 · 2022: 26 · 2021: 30 · 2020: 46 · 2019: 31 · 2018: 60 · 2017: 28 · 2016: 25 · 2015: 37 · 2014: 19 · 2013: 24 · 2012: 13
- FWCI
- 12.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Epilepsia (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- epilepsy, neuropsychiatric disorders, depression, anxiety, psychosis, non-epileptic seizures, cognitive impairment, suicidality, pediatric epilepsy, intellectual disability, epilepsy surgery, Delphi consensus
- MeSH terms
- Adolescent, Adult, Anxiety Disorders, Mental Disorders, Child, Cognition Disorders, Depressive Disorder, Epilepsy, Humans, Intellectual Disability, Psychotic Disorders, Practice Guidelines as Topic
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