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Antisocial Personality Disorder and Alcohol‐Induced Aggression
Abstract
This study compared the effects of alcohol on aggressive responding between subjects with antisocial personality disorder (ASPD) and subjects without ASPD. Eighteen alcohol drinking subjects (10 subjects without ASPD and 8 subjects with ASPD) underwent testing on a laboratory measure of aggression, the Point Subtraction Aggression Paradigm, after consumption of placebo and three doses of alcohol (0.25 g/kg, 0.5 g/kg, and 1.0 g/kg). There was a significant difference in the effect of alcohol on aggressive responding on the Point Subtraction Aggression Paradigm between subjects with ASPD and subjects without ASPD. Subjects with ASPD had a greater increase in aggressive responding after alcohol, compared with non‐ASPD subjects. There was no difference between the two groups in the effect of alcohol on monetary‐reinforced responding.
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Alcohol disproportionately increases aggression in individuals with ASPD.
“Laboratory research confirms that alcohol disproportionately increases aggression in individuals with ASPD.”
From Decoding the bidirectional links between alcohol misuse and aggression: toward a unified translational framework (2026) · cites this paper as Moeller et al. 1998
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Cited by
Sorted by citations
Further evidence for the validity of the Taylor Aggression Paradigm
Giancola, P. R., & Parrott, D. J. (2008) · Aggressive Behavior · doi:10.1002/ab.20235 · Cited by 218
Russell, N. M., Frier, M. D., Bortolato, M., & Mangieri, R. A. (2026) · Psychopharmacology · doi:10.1007/s00213-025-06938-0 · Cited by 3
Metadata
- Authors
- Moeller, F. G., Dougherty, D. M., Lane, S. D., Steinberg, J. L., & Cherek, D. R.
- Affiliations
- The University of Texas at Austin (US)
- Corresponding author
- Moeller, F. Gerard
- Venue
- Alcoholism: Clinical and Experimental Research
- Publisher
- Wiley
- Published
- 1998-12
- Volume
- 22
- Issue
- 9
- Pages
- 1898-1902
- ISSN
- 0145-6008 (ISSN-L)
- 1530-0277
- OpenAlex
- W2004061334
- Cited by
- 92
- References
- 0
- Citations by year
- 2025: 3 · 2023: 5 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Alcoholism Clinical and Experimental Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R29AA010095, R01AA010828)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Social Sciences › Psychology › Social Psychology › Bullying, Victimization, and Aggression
- Keywords
- antisocial personality disorder, alcohol-induced aggression, alcohol intoxication, Point Subtraction Aggression Paradigm, monetary reinforcement, alcohol dose-response
- MeSH terms
- Adult, Aggression, Alcohol Drinking, Ethanol, Alcoholic Intoxication, Antisocial Personality Disorder, Dose-Response Relationship, Drug, Humans, Male, Motivation, Violence
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