Neurotoxicity and neurocognitive impairments with alcohol and drug-use disorders: potential roles in addiction and recovery
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This article represents the proceedings of a symposium at the 2000 RSA Meeting in Denver, Colorado. The organisers/chairs were Stephen C. Bowden and Fulton T. Crews. The presentations were (1) Age, genetic and other factors that increase risk of alcoholism also increase alcohol-induced neurotoxicity, by Fulton T. Crews; (2) A neurocognitive moderation model of addictions treatment response, by Marsha E. Bates; (3) The relationship of neurocognitive impairment and longitudinal treatment outcome among substance-abusing patients, by William Fals-Stewart; and (4) Treatment of cognition in detoxifying alcohol-dependent participants, by Margaret L. Ambrose.
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This lower brain volume occurs without major nutritional deficiencies, though nutritional deficiencies can cause neurodegeneration and may contribute.
“This occurs in the absence of major nutritional deficiencies, although nutritional deficiencies can cause neurodegeneration and could contribute to alcoholic degeneration (Bowden et al., 2001).”
From Impulsivity, frontal lobes and risk for addiction (2009) · cites this paper as Bowden et al., 2001
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References 28 · Cited by 63
Research works printed but not linked: 2
- Bates M, Convit A (1999) Neuropsychology and neuroimaging of alcohol and drug abuse, in Neuropsychological Functions in Psychiatric Disorders (Calev A ed), pp 342-375. American Psychiatric Press, Washington DC.
- Heaton RK, Thompson LL, Nelson LM, Filley CM, Franklin GM (1990) Brief and intermediate length screening of neuropsychological impair- ment in multiple sclerosis, in Multiple Sclerosis: A Neuropsychological Perspective (Rao SM ed), pp 149 -160. Oxford University Press, New York.
- Authors
- Bowden, S. C., Crews, F. T., Bates, M. E., Fals‐Stewart, W., & Ambrose, M. L.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- Corresponding author
- Bowden, Stephen C.
- Venue
- Alcoholism Clinical and Experimental Research
- Publisher
- Wiley
- Published
- 2001-02
- Volume
- 25
- Issue
- 2
- Pages
- 317-321
- ISSN
- 0145-6008 (ISSN-L)
- 1530-0277
- OpenAlex
- W2135826894
- Cited by
- 63
- References
- 28
- Citations by year
- 2025: 2 · 2024: 1 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 1 · 2018: 4 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 4 · 2013: 2 · 2012: 5
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Alcoholism Clinical and Experimental Research (publishedVersion)
- PubMed (publishedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Funders
- Alpha Foundation for the Improvement of Mine Safety and Health
- Medical Research Council
- National Health and Medical Research Council
- National Institute on Alcohol Abuse and Alcoholism (P50 AA08747, AA-11594, P50AA008747, R01AA011594)
- National Institute on Drug Abuse (R01DA012189, R01DA12189-0A1)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Neurology › Alcoholism and Thiamine Deficiency
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Keywords
- alcohol neurotoxicity, neurocognitive impairment, substance use disorders, addiction, recovery, alcoholism risk factors, age, genetic factors, treatment response, moderation model, alcohol detoxification, cognitive intervention
- MeSH terms
- Alcoholism, Animals, Brain, Cognition Disorders, Humans, Nervous System Diseases, Thiamine, Substance-Related Disorders
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