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Cited by 660Intensive Care Unit Cognitive DisordersAnesthesia and Sedative AgentsAlcoholism and Thiamine Deficiency

The DOI matches its Crossref record; 30 of the 31 references it cites were found in a registry or an index.

Delirium and Its Motoric Subtypes: A Study of 614 Critically Ill Patients

Peterson, Josh F., Pun, Brenda T., Dittus, Robert S., Thomason, Jason W. W., Jackson, James C., Shintani, Ayumi K., Ely, E. Wesley·2006·Journal of the American Geriatrics Society
DOI 10.1111/j.1532-5415.2005.00621.x
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Abstract

OBJECTIVES: To describe the motoric subtypes of delirium in critically ill patients and compare patients aged 65 and older with a younger cohort. DESIGN: Prospective cohort study. SETTING: The medical intensive care unit (MICU) of a tertiary care academic medical center. PARTICIPANTS: Six hundred fourteen MICU patients admitted during a process improvement initiative to monitor levels of sedation and delirium. MEASUREMENTS: MICU nursing staff assessed delirium and level of consciousness in all MICU patients at least once per 12-hour shift using the Confusion Assessment Method for the Intensive Care Unit and the Richmond Agitation-Sedation Scale. Delirium episodes were categorized as hypoactive, hyperactive, and mixed type. RESULTS: Delirium was detected in 112 of 156 (71.8%) subjects aged 65 and older and 263 of 458 (57.4%) subjects younger than 65. Mixed type was most common (54.9%), followed by hypoactive delirium (43.5%) and purely hyperactive delirium (1.6%). Patients aged 65 and older experienced hypoactive delirium at a greater rate than younger patients (41.0% vs 21.6%, P<.001) and never experienced hyperactive delirium. Older age was strongly and independently associated with hypoactive delirium (adjusted odds ratio=3.0, 95% confidence interval=1.7-5.3), compared with no delirium in a model that adjusted for other important determinants of delirium including severity of illness, sedative medication use, and ventilation status. CONCLUSION: Older age is a strong predictor of hypoactive delirium in MICU patients, and this motoric subtype of delirium may be missed in the absence of active monitoring.

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Crossref · 10.1111/j.1532-5415.2005.00621.x

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Research works printed but not linked: 3

  1. McNicoll L, 2004, One‐year outcomes following delirium in older ICU patients [abstract], J Am Geriatr Soc, 52, S2
  2. Peterson JF, 2003, The prevalence of hypoactive, hyperactive, and mixed type delirium in medical ICU patients, J Am Geriatr Soc, 51, S174
  3. Truman B, 2003, Large‐scale implementation of delirium and sedation monitoring in the ICU, Am J Crit Care, 12, 288

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Metadata

Authors
Peterson, J. F., Pun, B. T., Dittus, R. S., Thomason, J. W. W., Jackson, J. C., Shintani, A. K., & Ely, E. W.
Affiliations
  • Vanderbilt University Medical Center (US)
  • VA Tennessee Valley Healthcare System (US)
Corresponding author
  • Peterson, Josh F.
  • Ely, E. Wesley
ORCID
Venue
Journal of the American Geriatrics Society
Publisher
Wiley
Published
2006-03
Volume
54
Issue
3
Pages
479-484
ISSN
  • 0002-8614 (ISSN-L)
  • 1532-5415
DOI
10.1111/j.1532-5415.2005.00621.x
OpenAlex
W1505808688
Cited by
660
References
31
Citations by year
2026: 11 · 2025: 17 · 2024: 32 · 2023: 37 · 2022: 21 · 2021: 33 · 2020: 32 · 2019: 45 · 2018: 44 · 2017: 41 · 2016: 48 · 2015: 37 · 2014: 29 · 2013: 42 · 2012: 44
FWCI
27.31
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Journal of the American Geriatrics Society (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Eli Lilly and Company
  • Pfizer
Topics
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
  • Health Sciences › Medicine › Clinical Neurology › Alcoholism and Thiamine Deficiency
Keywords
delirium, hypoactive delirium, hyperactive delirium, mixed delirium, critically ill patients, older adults, intensive care unit, age as predictor, sedation, level of consciousness, delirium monitoring
MeSH terms
Age Factors, Aged, Critical Care, Delirium, Female, Follow-Up Studies, Humans, Male, Motor Activity, Prognosis, Prospective Studies, Severity of Illness Index, Incidence, Prevalence, Critical Illness

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