The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Subcutaneous Botulinum Toxin for Chronic Post‐Thoracotomy Pain
Abstract
Objective: Botulinum toxin is a neurotoxin that has been widely used in chronic pain for the treatment of multiple conditions with a component of localized muscle spasm. Recent studies suggest that botulinum toxin is effective in the treatment of neuropathic pain syndromes such as post‐herpetic neuralgia. Case Report: We report the case of a 67‐year‐old man who underwent atypical segmentectomy of a right lower lobe lung nodule. The patient was referred to our pain management department with a of 2‐year history persistent pain along the thoracotomy scar having a predominantly neuropathic component, refractory to standard treatments. He was successfully treated with subcutaneous botulinum toxin type A. Discussion: On the basics of our own experience and on the analysis of the reports published in the literature, fractioned subcutaneous injections of botulinum toxin may be useful for the treatment of various chronic localized pain conditions including chronic post‐thoracotomy pain.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Botulinum toxin injections in the painful areas of chronic post-thoracotomy pain have been reported to provide significant pain relief for patients unresponsive to oral therapy [68].”
From Chronic postsurgical pain: current evidence for prevention and management (2018) · cites this paper as [68]
Citations
Cites
Treede (2008) · doi:10.1212/01.wnl.0000282763.29778.59 · Cited by 2,746
Pharmacologic management of neuropathic pain: Evidence-based recommendations
Dworkin, R. H., O’Connor, A. B., Backonja, M., Farrar, J. T., Finnerup, N. B., Jensen, T. S., Kalso, E. A., Loeser, J. D., Miaskowski, C., Nurmikko, T. J., et al. (2007) · Pain · doi:10.1016/j.pain.2007.08.033 · Cited by 2,126
Subcutaneous administration of botulinum toxin A reduces formalin-induced pain
Cui, M., Khanijou, S., Rubino, J., & Aoki, K. R. (2003) · Pain · doi:10.1016/j.pain.2003.10.008 · Cited by 675
Botulinum toxin type a induces direct analgesic effects in chronic neuropathic pain
Ranoux, D., Attal, N., Morain, F., & Bouhassira, D. (2008) · Annals of Neurology · doi:10.1002/ana.21427 · Cited by 456
Long-Distance Retrograde Effects of Botulinum Neurotoxin A
Antonucci, F., Rossi, C., Gianfranceschi, L., Rossetto, O., & Caleo, M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0375-08.2008 · Cited by 454
Long-Term Postthoracotomy Pain
Dajczman, E., Gordon, A. G., Kreisman, H., & Wolkove, N. (1991) · CHEST Journal · doi:10.1378/chest.99.2.270 · Cited by 358
Wildgaard, K., Ravn, J. B., & Kehlet, H. (2009) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2009.02.005 · Cited by 350
Botulinum toxin for diabetic neuropathic pain
Yuan, R., Sheu, J. J., Yu, J., Chen, W.-T., Tseng, I. J., Chang, H., & Hu, C. (2009) · Neurology · doi:10.1212/01.wnl.0000345968.05959.cf · Cited by 279
Only Half of the Chronic Pain After Thoracic Surgery Shows a Neuropathic Component
Steegers, M. A. H., Snik, D. M., Verhagen, A. F. T. M., van der Drift, M. A., & Wilder‐Smith, O. H. G. (2008) · Journal of Pain · doi:10.1016/j.jpain.2008.05.009 · Cited by 258
Chronic post‐thoracotomy pain: a retrospective study
Pluijms, W. A., Steegers, M. A. H., Verhagen, A. F. T. M., Scheffer, G. J., & Wilder‐Smith, O. H. G. (2006) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2006.01065.x · Cited by 237
Byrnes, M. L. (1998) · Brain · doi:10.1093/brain/121.5.977 · Cited by 231
Subcutaneous Injection of Botulinum Toxin A Is Beneficial in Postherpetic Neuralgia
Xiao, L., Mackey, S., Hui, H., Xong, D., Zhang, Q., & Zhang, D. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.01003.x · Cited by 197
Gazerani, P., Pedersen, N. S., Staahl, C., et al. (2008) · Pain · doi:10.1016/j.pain.2008.10.005 · Cited by 175
An open study of botulinum-A toxin treatment of trigeminal neuralgia
Piovesan, É. J., Teive, H. G., Kowacs, P. A., Coletta, M. V. D., Werneck, L. C., & Silberstein, S. D. (2005) · Neurology · doi:10.1212/01.wnl.0000180940.98815.74 · Cited by 167
Smith, C. P., Vemulakonda, V. M., Kiss, S., Boone, T. B., & Somogyi, G. T. (2005) · Neurochemistry International · doi:10.1016/j.neuint.2005.04.021 · Cited by 143
A study exploring the role of intercostal nerve damage in chronic pain after thoracic surgery
Maguire, M. F., Latter, J. A., Mahajan, R., Beggs, F. D., & Duffy, J. P. (2006) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2006.03.031 · Cited by 133
Sympathetic block with botulinum toxin to treat complex regional pain syndrome
Carroll, I. R., Clark, J. D., & Mackey, S. (2009) · Annals of Neurology · doi:10.1002/ana.21601 · Cited by 129
The use of botulinum toxin for the treatment of chronic facial pain
Borodic, G. E., & Acquadro, M. A. (2002) · Journal of Pain · doi:10.1054/jpai.2002.27142 · Cited by 103
Botulinum Toxin Occipital Nerve Block for the Treatment of Severe Occipital Neuralgia: A Case Series
Kapural, L., Stillman, M. J., Kapural, M., McIntyre, P. J., Guirgius, M., & Mekhail, N. A. (2007) · Pain Practice · doi:10.1111/j.1533-2500.2007.00150.x · Cited by 94
Botox produces functional weakness in non-injected muscles adjacent to the target muscle
Yaraskavitch, M., Leonard, T. R., & Herzog, W. (2008) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2007.11.016 · Cited by 87
Botulinum Toxin type A reduces capsaicin-evoked pain and neurogenic vasodilatation in human skin
Tugnoli, V., Capone, J. G., Eleopra, R., et al. (2006) · Pain · doi:10.1016/j.pain.2006.10.030 · Cited by 81
Botulinum Toxin A Relieved Neuropathic Pain in a Case of Post-Herpetic Neuralgia
Liu, H.-T., Tsai, S., Kao, M., et al. (2006) · Pain Medicine · doi:10.1111/j.1526-4637.2006.00100.x · Cited by 74
Botulinum Toxin A Improved Burning Pain and Allodynia in Two Patients With Spinal Cord Pathology
Jabbari, B., Maher, N., & Difazio, M. P. (2003) · Pain Medicine · doi:10.1046/j.1526-4637.2003.03013.x · Cited by 59
Severe Post-herpetic Neuralgia Successfully Treated with Botulinum Toxin A: Three Case Reports
Sotiriou, E., Apalla, Z., Panagiotidou, D., & Ioannidis, D. (2009) · Acta Dermato Venereologica · doi:10.2340/00015555-0609 · Cited by 39
[Botulinum toxin type A in the treatment of neuropathic pain in a case of postherpetic neuralgia].
Huete, C. R., & Bermejo, P. E. (2008) · PubMed · Cited by 30
Other indications of botulinum toxin therapy
Jost, W. H. (2006) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01448.x · Cited by 27
Botulinum toxin for neuropathic pain?
Apfel, S. C. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a412b2 · Cited by 8
Chronic post-thoracotomy pain syndrome
Strebel, B. M., & Ross, S. (2007) · Canadian Medical Association Journal · doi:10.1503/cmaj.061196 · Cited by 6
Cited by
Sorted by citations
Chronic postsurgical pain: current evidence for prevention and management
Thapa, P., & Euasobhon, P. (2018) · The Korean Journal of Pain · doi:10.3344/kjp.2018.31.3.155 · Cited by 177
Metadata
- Authors
- Fabregat, G., Asensio‐Samper, J. M., Palmisani, S., Villanueva‐Pérez, V. L., & De Andrés, J.
- Affiliations
- Hospital General Universitario De Valencia (ES)
- ORCID
- Palmisani, Stefano
- Venue
- Pain Practice
- Publisher
- Wiley
- Published
- 2012-06-21
- Volume
- 13
- Issue
- 3
- Pages
- 231-234
- ISSN
- 1530-7085 (ISSN-L)
- 1533-2500
- OpenAlex
- W1932933802
- Cited by
- 35
- References
- 28
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 5 · 2016: 1 · 2015: 9 · 2014: 1 · 2013: 2
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Botulinum Toxin and Related Neurological Disorders
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Keywords
- botulinum toxin type A, subcutaneous injection, chronic post-thoracotomy pain, neuropathic pain, segmentectomy, refractory pain, pulmonary nodules
- MeSH terms
- Aged, Carcinoma, Squamous Cell, Humans, Injections, Subcutaneous, Lung Neoplasms, Male, Neuralgia, Neuromuscular Agents, Postoperative Pain, Thoracotomy, Botulinum Toxins, Type A
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
