Cited by 168Cardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studiesAtrial Fibrillation Management and Outcomes

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Ventricular Fibrillation and Sudden Death After Radiofrequency Catheter Ablation of the Atrioventricular Junction

GEELEN, PETER, BRUGADA, JOSEP, ANDRIES, ERIK, BRUGADA, PEDRO·1997·Pacing and Clinical Electrophysiology

DOI 10.1111/j.1540-8159.1997.tb06179.x

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Abstract

Two hundred thirty-five patients underwent RF catheter ablation of AV conduction for symptomatic drug refractory AF (84%), atrial flutter (9%), and atrial tachycardia (7%). In the first 100 patients, postablation pacing was not prospectively set at any specific rate and was always < or = 70 beats/min. In the next 135 patients, postablation pacing was prospectively set at 90 beats/min for 1-3 months. Six of the first 100 patients (6%) had VF or sudden death after the RF procedure and none (0%) of the next 135 patients did (P < 0.05). One of the six patients had recurrent VF 4 days after the ablation. Five patients were successfully resuscitated and one patient died. There were no statistically significant differences between patients with and without (aborted) sudden death or between the first 100 and the next 135 patients with respect to age, sex, underlying heart disease, EF, number of RF applications, or left-or right-sided approach of the procedure. VF mostly occurred during episodes of slow ventricular escape rhythms or during slow ventricular pacing. We conclude that malignant ventricular arrhythmias and sudden death are possible complications of RF ablation of the AV function. The mechanism of these complications could have a bradycardia dependent nature and it seems that the occurrence of malignant arrhythmias can be prevented by temporarily pacing the heart at relatively fast rates immediately after ablation.

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Authors: GEELEN, P., BRUGADA, J., ANDRIES, E., & BRUGADA, P.
Affiliations: Onze Lieve Vrouwziekenhuis Hospital (BE)
Corresponding author: BRUGADA, PEDRO
ORCID: ANDRIES, ERIK
BRUGADA, PEDRO
Venue: Pacing and Clinical Electrophysiology
Publisher: Wiley
Published: 1997-02
Volume: 20
Issue: 2
Pages: 343-348
ISSN: 0147-8389 (ISSN-L)
1540-8159
DOI: 10.1111/j.1540-8159.1997.tb06179.x
OpenAlex: W2010906453
Cited by: 168
References: 7
Citations by year: 2026: 1 · 2025: 6 · 2024: 7 · 2023: 3 · 2020: 1 · 2019: 6 · 2018: 5 · 2017: 3 · 2016: 7 · 2015: 4 · 2014: 5 · 2013: 3 · 2012: 6
FWCI: 8.55
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 3436 d)
Locations: Pacing and Clinical Electrophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords: ventricular fibrillation, sudden cardiac death, radiofrequency catheter ablation, atrioventricular junction, atrioventricular block, atrial fibrillation, atrial flutter, atrial tachycardia, malignant ventricular arrhythmias, procedural complications
MeSH terms: Aged, Atrial Flutter, Atrioventricular Node, Female, Humans, Male, Middle Aged, Ventricular Fibrillation, Death, Sudden, Cardiac, Catheter Ablation

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Ventricular Fibrillation and Sudden Death After Radiofrequency Catheter Ablation of the Atrioventricular Junction

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