Cited by 134Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

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Prevalence, predictors and prognosis of atrial fibrillation early after pulmonary vein isolation: Findings from 3 months of continuous automatic ECG loop recordings

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JOSHI, SANDEEP, CHOI, ANDREW D., KAMATH, GANESH S., RAISZADEH, FARBOD, MARRERO, DANIEL, BADHEKA, APURVA, MITTAL, SUNEET, STEINBERG, JONATHAN S.·2009·Journal of Cardiovascular Electrophysiology

DOI 10.1111/j.1540-8167.2009.01506.x

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Abstract

Introduction: Following pulmonary vein isolation (PVI) for atrial fibrillation (AF), early recurrences are frequent, benign and classified as a part of a “blanking period.” This study characterizes early recurrences and determines implications of early AF following PVI. Methods and Results: Seventy‐two consecutive patients (59.8 ± 10.7 years, 69% male) were studied following PVI for paroxysmal or persistent AF. Subjects were fitted with an external loop recorder for automatic, continuous detection of AF recurrence for 3 months. AF prevalence was highest 2 weeks after PVI (54%) and declined to an eventual low of 22%. A significant number (488, 34%) of recurrences were asymptomatic; however, all patients with ≥1 AF event had ≥1 symptomatic event. No clear predictor of early recurrence was identified. Forty‐seven (65%) patients had at least 1 AF episode, predominantly (39 of 47 patients, 83%) within 2 weeks of PVI. Of the 33 patients who did not experience AF within the first 2 weeks, 85% (28/33) were complete responders (P = 0.03) at 12 months. Recurrence at any time within 3 months was not associated with procedural success or failure. Conclusions: Early AF recurrence peaks within the first few weeks after PVI, but continues at a lower level until the completion of monitoring. A blanking period of 3 months is justified to identify patients with AF recurrences that do not portend procedure failure. Freedom from AF in the first 2 weeks following ablation significantly predicts long‐term AF freedom.

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Authors: JOSHI, S., CHOI, A. D., KAMATH, G. S., RAISZADEH, F., MARRERO, D., BADHEKA, A., MITTAL, S., & STEINBERG, J. S.
Affiliations: St. Luke's-Roosevelt Hospital Center (US)
Corresponding author: STEINBERG, JONATHAN S.
ORCID: JOSHI, SANDEEP
CHOI, ANDREW D.
KAMATH, GANESH S.
RAISZADEH, FARBOD
MARRERO, DANIEL
MITTAL, SUNEET
STEINBERG, JONATHAN S.
Venue: Journal of Cardiovascular Electrophysiology
Publisher: Wiley
Published: 2009-10
Volume: 20
Issue: 10
Pages: 1089-1094
ISSN: 1045-3873 (ISSN-L)
1540-8167
DOI: 10.1111/j.1540-8167.2009.01506.x
OpenAlex: W2036327948
Cited by: 134
References: 15
Citations by year: 2026: 4 · 2025: 5 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 9 · 2017: 15 · 2016: 15 · 2015: 9 · 2014: 11 · 2013: 10 · 2012: 11
FWCI: 6.04
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of Cardiovascular Electrophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords: atrial fibrillation, pulmonary vein isolation, catheter ablation, early recurrence, blanking period, external loop recorder, continuous ECG monitoring, asymptomatic recurrence, predictors of recurrence, long-term prognosis, procedural success
MeSH terms: Atrial Fibrillation, Female, Heart Conduction System, Humans, Male, Middle Aged, Prognosis, Pulmonary Veins, Risk Factors, Electrocardiography, Ambulatory, Prevalence, Treatment Outcome, Catheter Ablation, Risk Assessment

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Prevalence, predictors and prognosis of atrial fibrillation early after pulmonary vein isolation: Findings from 3 months of continuous automatic ECG loop recordings

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