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Magnetocardiography Predicts Coronary Artery Disease in Patients with Acute Chest Pain
Open accessAbstract
Background: The value of magnetocardiography (MCG) for the detection of cardiac electrical disturbances associated with myocardial ischemia was studied. Methods: Sensitivity and predictivity of admission MCG for the presence of coronary artery disease (CAD) were prospectively evaluated in 264 consecutive patients presenting with acute chest pain and without ST‐segment elevation. MCG findings were compared with 12‐lead ECG, echocardiography (ECHO), and troponin‐I in a head‐to‐head design. Coronary angiography was used for CAD diagnosis. Results: The visual assessment of magnetocardiograms by the experienced reader (R1) was superior to that by the unexperienced reader (R2) and superior to the automated computer analysis. Specificity and positive predictive value of MCG by R1 were comparable with those of ECG and troponin‐I (>90%), while ECHO specificity and ECHO positive predictive value were lower (76.2% and 87.9%, respectively). Sensitivity and negative predictive value of MCG were twice as high as those in the ECG, troponin‐I, and ECHO tests. Conclusion: For the prediction of CAD in patients presenting with acute chest pain and without ST‐segment elevation, an admission MCG test was superior to an admission ECG, ECHO, and troponin‐I. The results of the study, however, are applicable only to a highly selected population comprising patients in whom immediate coronary angiography can be performed based on their clinical course in the hospital.
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“As another, the ability to detect repolarization abnormalities (potential heart infarction) at rest, even in patients with non-specific 12-lead ECG and normal troponine enzyme test [28].”
From Biomagnetism using SQUIDs: status and perspectives (2006) · cites this paper as [28]
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Magnetocardiography in Diagnosis of Stress-Induced Cardiomyopathy
Hunter, D. D., Sularz, A., Adi, M. Z., Al-Abcha, A. K., Matin, A., Bakharev, A., Vanmeter, D. E., Alkhouli, M. A., & Hevesi, S. A. (2025) · JACC Case Reports · doi:10.1016/j.jaccas.2025.104037
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Metadata
- Authors
- Park, J., Hill, P. M., Chung, N., Hugenholtz, P. G., & Jung, F.
- Affiliations
- Johns Hopkins University (US)
- Yonsei University (KR)
- Saarland University (DE)
- Venue
- Annals of Noninvasive Electrocardiology
- Publisher
- Wiley
- Published
- 2005-07
- Volume
- 10
- Issue
- 3
- Pages
- 312-323
- ISSN
- 1082-720X (ISSN-L)
- 1542-474X
- PMC
- PMC6932599
- OpenAlex
- W2068244737
- Cited by
- 109
- References
- 20
- Citations by year
- 2026: 10 · 2025: 12 · 2024: 7 · 2023: 4 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 2 · 2014: 3 · 2013: 4 · 2012: 3
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of Noninvasive Electrocardiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Keywords
- magnetocardiography, coronary artery disease, acute chest pain, non-ST-segment elevation, myocardial ischemia, diagnostic accuracy, sensitivity and specificity, positive predictive value, 12-lead ECG, echocardiography, troponin I
- MeSH terms
- Acute Disease, Aged, Chest Pain, Coronary Disease, Echocardiography, Electrocardiography, Female, Humans, Magnetics, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Sensitivity and Specificity, Coronary Angiography
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