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Surrogate consent by family members for out-of-hospital cardiac arrest research
Abstract
Objectives To evaluate the availability of family members of potential subjects to provide consent for participation in out-of-hospital cardiac arrest (OOHCA) research and to estimate the time required to contact a family member. Methods This study was a prospective observational study of adult patients (>18 years old) with nontraumatic OOHCA treated by an urban emergency medical service. Emergency medicine resident physicians responded to each scene and noted the presence of family members. A subsequent convenience sample of family members answered standardized questions about their ability to provide consent for research participation on behalf of the patient. Results Physicians were present at 100 of the 112 adult medical cardiac arrests during the study period. A family member was present at 57% of the scenes (95% CI = 47% to 67%). Patients with family present were older and were less likely to have bystander cardiopulmonary resuscitation (CPR) or live in a nursing home. The mean time (+/-SE) from emergency dispatch to family contact was 24.40 (+/-2.60) minutes and from physician arrival to family contact was 2.45 (+/-0.87) minutes (n = 20). Eight of 13 family members were willing to enroll the patient into a resuscitation study, but five family members were unable to understand the explanation of informed consent. Conclusions Family members were present for an unrepresentative subset of OOHCA cases, and were contacted after the therapeutic window for many interventions.…
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Information about whether a patient collapse was witnessed or not, cardiac arrest location, certain aspects of emergency care organisation, patient characteristics, treating hospital characteristics, downtimes, and treatments administered may also be collected.
“Information about whether a patient collapse was witnessed or not, cardiac arrest location, certain aspects of emergency care organisation (e.g. availability of dispatcherassisted bystander CPR), patient characteristics (e.g. age, sex, race, and comorbidities), treating hospital characteristics (e.g. bed size and teaching status), downtimes (e.g. time from collapse to first shock), and treatments”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [357]
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Research works printed but not linked: 8
- 10.1001/jama.281.13.1182 · DOI
- Biros MH, 1995, Informed consent in emergency research: consensus statement from the Coalition Conference of Acute Resuscitation and Critical Care Researchers., JAMA, 273, 1283, 10.1001/jama.1995.03520400053044 · DOI
- 1991, Protection of Human Subjects (Exception to Informed Consent)
- 1991, Protection of Human Subjects (Waiver of Informed Consent)
- 10.1056/NEJM199308263290902 · DOI
- 10.1080/10903120090941498 · DOI
- Taylor EM, 1998, Do our patients understand? A comparison of understanding in adult inpatients and schoolchildren., N Z Med J, 111, 449
- 10.1111/j.1553-2712.1999.tb01205.x · DOI
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European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions
Mentzelopoulos, S. D., Couper, K., Voorde, P. V. D., Druwé, P., Blom, M., Perkins, G. D., Lulic, I., Djakow, J., Raffay, V., Lilja, G., et al. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.02.017 · Cited by 246
McClure, K. B. (2003) · Academic Emergency Medicine · doi:10.1197/aemj.10.4.352 · Cited by 110
Metadata
- Authors
- Hsieh, M., Dailey, M. W., & Callaway, C. W.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- Hsieh, Margaret
- Venue
- Academic Emergency Medicine
- Publisher
- Wiley
- Published
- 2001-08
- Volume
- 8
- Issue
- 8
- Pages
- 851-853
- ISSN
- 1069-6563 (ISSN-L)
- 1553-2712
- OpenAlex
- W2017869060
- Cited by
- 45
- References
- 0
- Citations by year
- 2026: 1 · 2025: 2 · 2021: 5 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 1 · 2012: 1
- FWCI
- 1.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Academic Emergency Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- out-of-hospital cardiac arrest, surrogate consent, family members, informed consent, research participation, bystander CPR, emergency medical services, resuscitation research, therapeutic window
- MeSH terms
- Adult, Ambulatory Care, Decision Making, Evaluation Studies as Topic, Family, Heart Arrest, Humans, Prospective Studies, Cardiopulmonary Resuscitation, Third-Party Consent
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