The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Tissue engineering of blood vessel
Open accessAbstract
Introduction Components of blood vessel Principle of vessel engineering Seeding cells sources Biodegradable scaffolds Vessel engineering in vitro Clinical applications Future perspectives Vascular grafts are in large demand for coronary and peripheral bypass surgeries. Although synthetic grafts have been developed, replacement of vessels with purely synthetic polymeric conduits often leads to the failure of such graft, especially in the grafts less than 6 mm in diameter or in the areas of low blood flow, mainly due to the early formation of thrombosis. Moreover, the commonly used materials lack growth potential, and long‐term results have revealed several material‐related failures, such as stenosis, thromboembolization, calcium deposition and infection. Tissue engineering has become a promising approach for generating a bio‐compatible vessel graft with growth potential. Since the first success of constructing blood vessels with collagen and cultured vascular cells by Weinberg and Bell, there has been considerable progress in the area of vessel engineering. To date, tissue‐ engineered blood vessels (TEBVs) could be successfully constructed in vitro, and be used to repair the vascular defects in animal models. This review describes the major progress in the field, including the seeding cell sources, the biodegradable scaffolds, the construction technologies, as well as the encouraging achievements in clinical applications. The remaining challenges are also discussed.
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Cites
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies
Zuk, P. A., Zhu, M., Mizuno, H., Huang, J., Futrell, J. W., Katz, A. J., Benhaim, P., Lorenz, H. P., & Hedrick, M. H. (2001) · Tissue Engineering · doi:10.1089/107632701300062859 · Cited by 7,956
Asahara, T., Takahashi, T., Masuda, H., Kalka, C., Chen, D., Iwaguro, H., Inai, Y., Silver, M., & Isner, J. M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.14.3964 · Cited by 1,851
Functional Arteries Grown in Vitro
Niklason, L. E., Gao, J., Abbott, W. M., Hirschi, K. K., Houser, S. L., Marini, R. P., & Langer, R. (1999) · Science · doi:10.1126/science.284.5413.489 · Cited by 1,767
Ingram, D. A., Mead, L. E., Tanaka, H., Meade, V. M., Fenoglio, A., Mortell, K. E., Pollok, K. E., Ferkowicz, M. J., Gilley, D. P., & Yöder, M. C. (2004) · Blood · doi:10.1182/blood-2004-04-1396 · Cited by 1,534
A common precursor for hematopoietic and endothelial cells
Choi, K., Kennedy, M., Kazarov, A. R., Papadimitriou, J. C., & Keller, G. M. (1998) · Development · doi:10.1242/dev.125.4.725 · Cited by 1,435
A completely biological tissue-engineered human blood vessel
L’Heureux, N., Pâquet, S., Labbé, R., Germain, L., & Auger, F. A. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.1.47 · Cited by 1,388
Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
Yamashita, J. K., Itoh, H., Hirashima, M., Ogawa, M., Nishikawa, S., Yurugi, T., Naito, M., Nakao, K., & Nishikawa, S.-I. (2000) · Nature · doi:10.1038/35040568 · Cited by 1,348
A Blood Vessel Model Constructed from Collagen and Cultured Vascular Cells
Weinberg, C. B., & Bell, E. (1986) · Science · doi:10.1126/science.2934816 · Cited by 1,247
Human tissue-engineered blood vessels for adult arterial revascularization
L’Heureux, N., Dusserre, N., König, G., Victor, B. E., Keire, P. A., Wight, T. N., Chronos, N. A. F., Kyles, A. E., Gregory, C. R., Hoyt, G. E., et al. (2006) · Nature Medicine · doi:10.1038/nm1364 · Cited by 1,083
Research works printed but not linked: 1
- KirklinJW Barratt‐BoyesBG.Ventricular Septal Defect and Pulmonary Stenosis or Atresia. In:KirklinJW Barratt‐BoyesBG editors.2nded.Cardiac surgery. New York :Churchill Livingstone;1993. pp.861–1612.
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Items 201–217 of 217
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Kiros, S. (2016) · Scholarship@Western (Western University)
Pashneh‐Tala, S. (2017) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Hybrid bioengineering of tubular constructs for esophagus by melt-drawing and 3D bioprinting
Tan, Y. J. (2018) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/73186
The Role of Autophagy in Vascular Biology and Atherosclerosis
Perrotta, I. D. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805253-2.00014-6
Tubular Tissue Engineering Based on Microfluidics
Tang, L., Zheng, W., & Jiang, X. (2018) · Wiley eBooks · doi:10.1002/9781119390350.ch2
The Role of Cellular Architecture in Vascular Smooth Muscle Function and Mechanics
Win, Z. (2017) · University of Minnesota Digital Conservancy (University of Minnesota)
Saragó, A. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.10.2020.tde-18092020-075841
3D Bioprinting Methods and Techniques – A Information
Priya, K., & Chavhan, P. M. (2021) · doi:10.51521/ijmhr.2021.1106
Various Applications of 3D Printing in Biomedical Sciences and Technology.
ks, S. (2021) · SPAST Abstracts
Angiogenesis induction by natural and synthetic polymers
Hosseini, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821867-9.00018-4
Off-the-shelf vasculature: Biofabrication of compliant decellularized vascular grafts
Weekes, A. (2024) · Queensland University of Technology · doi:10.5204/thesis.eprints.250815
Validation pré-clinique d'un produit d'ingénierie vasculaire à base d'hydrogel de chitosane
Aussel, A. (2017) · theses.fr (ABES) · doi:10.70675/cd31a572z7ab3z44b4za98bze5efdce06580
Öztürk, S., Elçin, A. E., & Elçin, Y. M. (2026) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-032-30294-6_7
Metadata
- Authors
- Zhang, W. J., Liu, W., Cui, L., & Cao, Y.
- Affiliations
- Shanghai Jiao Tong University (CN)
- Corresponding author
- Cao, Yilin
- Venue
- Journal of Cellular and Molecular Medicine
- Publisher
- Wiley
- Published
- 2007-09
- Volume
- 11
- Issue
- 5
- Pages
- 945-957
- ISSN
- 1582-1838 (ISSN-L)
- 1582-4934
- PMC
- PMC4401266
- OpenAlex
- W3099528961
- Semantic Scholar
- b25eb347cafbc13414ee554f6424f15b9c910792
- Cited by
- 217
- References
- 117
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 13 · 2023: 11 · 2022: 10 · 2021: 21 · 2020: 12 · 2019: 17 · 2018: 13 · 2017: 18 · 2016: 7 · 2015: 13 · 2014: 12 · 2013: 10 · 2012: 11
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Cellular and Molecular Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Keywords
- tissue-engineered blood vessels, vascular grafts, coronary artery bypass grafting, graft failure, thrombosis, biodegradable scaffolds, stenosis, clinical translation
- MeSH terms
- Animals, Biocompatible Materials, Blood Vessels, Humans, Absorbable Implants, Tissue Engineering
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