Increased cerebrospinal fluid chitotriosidase index in patients with multiple sclerosis

Verbeek, M. M.; Notting, E. A.; Faas, B.; Claessens-Linskens, R.; Jongen, P. J. H.

doi:10.1111/j.1600-0404.2009.01242.x

Increased cerebrospinal fluid chitotriosidase index in patients with multiple sclerosis

Objective To investigate chitotriosidase (CTTS) activity in serum and cerebrospinal fluid (CSF) in multiple sclerosis (MS) patients in relation to disease course and CSF markers for immune activation or inflammation. Materials and methods We studied 80 patients with relapsing-remitting MS (RRMS),…