Cited by 28Iron Metabolism and DisordersFood and Agricultural SciencesPhytochemicals and Antioxidant Activities

Iron absorption from red and white wines

Bezwoda, W. R., Torrance, J. D., Bothwell, T. H., Macphail, A. P., Graham, B., Mills, W.·1985·Scandinavian Journal of Haematology

Abstract

Iron (3 mg) was added as ferrous sulphate to 2 dl red wine, white wine and 7 % alcohol and its absorption was then measured in 38 fasting male subjects. (The original concentrations of iron in the two wines were low, being 1.01–1.08 mg/l (red wine) and 0.13–0.20 (white wine)). The geometric mean absorption from red wine was only 20 % of that from the alcohol solution whilst more than 4 times as much was absorbed from white wine as from the alcohol. Direct comparison showed greater absorption from white wine (10.4 %) than from red wine (4.4 %). Removal of about 80 % of the polyphenols in red wine increased the geometric mean iron absorption from 1.9 % to 3.6 %. In vitro experiments indicated that iron was less soluble and less dialysable in red wines than in white wines. This was possibly due to the binding of iron to polyphenols in red wines. Electrophoretic studies suggested that the iron in white wines was complexed to hydroxy‐carboxylic acids.

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Crossref · 10.1111/j.1600-0609.1985.tb02243.x

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  • Red wine and cocoa, as well as various vegetables with a high polyphenol content, have been reported to inhibit Fe absorption.

    “Other beverages such as red wine (Bezwoda et al. 1985;Cook et al. 1995) and cocoa (Gillooly et al. 1984), as well as various vegetables with a high polyphenol content (Gillooly et al. 1983;Tuntawiroon et al. 1991), have also been reported to inhibit Fe absorption.”

    From Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages (1999) · cites this paper as Bezwoda et al. 1985

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Authors
Bezwoda, W. R., Torrance, J. D., Bothwell, T. H., Macphail, A. P., Graham, B., & Mills, W.
Affiliations
University of the Witwatersrand (ZA)
Corresponding author
Bothwell, T. H.
Venue
Scandinavian Journal of Haematology
Publisher
Wiley
Published
1985-02
Volume
34
Issue
2
Pages
121-127
ISSN
0036-553X (ISSN-L)
OpenAlex
W2042223105
Cited by
28
References
0
Citations by year
2025: 1 · 2022: 1 · 2018: 1 · 2015: 1 · 2012: 2
FWCI
0.51
Type
journal article
Language
en
Open access
closed
Locations
  • Scandinavian Journal of Haematology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
iron absorption, red wine, white wine, polyphenols, ferrous sulfate, iron solubility, hydroxy acids, dietary iron bioavailability, alcohol chemistry
MeSH terms
Absorption, Ethanol, Carboxylic Acids, Chromatography, Gel, Dialysis, Electrophoresis, Cellulose Acetate, Ferrous Compounds, Humans, Iron, Iron Radioisotopes, Male, Wine, In Vitro Techniques

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