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The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

Saliva as a diagnostic tool for periodontal disease: current state and future directions

Open access
Giannobile, William V., Beikler, Thomas, Kinney, Janet S., Ramseier, Christoph A., Morelli, Thiago, Wong, David T.·2009·Periodontology 2000

Abstract

In periodontics and implant dentistry, traditional clinical criteria are often insufficient for determining sites of active disease, for monitoring quantitatively the response to therapy or for measuring the degree of susceptibility to future disease progression.Saliva as a mirror of oral and systemic health is a valuable source for clinically relevant information because it contains biomarkers specific for the unique physiological aspects of periodontal / periimplant disease, and qualitative changes in the composition of these biomarkers could have diagnostic value by identifying patients with enhanced disease susceptibility, identifying sites with active disease, predicting sites that will have active disease in the future and / or serving as surrogate end points for monitoring the effectiveness of therapy.Although the diagnostic value of saliva has been recognized for some time (50, 51) and potential biomarkers of periodontal / peri-implant disease have been identified in saliva (39, 67, 74), most work carried out to date has failed to provide reliable aids to the clinician.However, the availability of more sophisticated analytic techniques give cause for optimism that saliva will eventually become the tool needed for more precise treatment planning.

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Metadata

Authors
Giannobile, W. V., Beikler, T., Kinney, J. S., Ramseier, C. A., Morelli, T., & Wong, D. T.
Venue
Periodontology 2000
Publisher
Wiley
Published
2009-04-08
Volume
50
Issue
1
Pages
52-64
ISSN
  • 0906-6713 (ISSN-L)
  • 1600-0757
OpenAlex
W2011705160
Cited by
381
References
70
FWCI
16.23
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Saliva as a diagnostic tool for periodontal disease: current state and future directions. https://app.cochat.ai/papers/10.1111/j.1600-0757.2008.00288.x
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Giannobile, W. V., Beikler, T., Kinney, J. S., Ramseier, C. A., Morelli, T., & Wong, D. T. (2009). Saliva as a diagnostic tool for periodontal disease: current state and future directions. Periodontology 2000. https://doi.org/10.1111/j.1600-0757.2008.00288.x

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