The DOI matches its Crossref record.
The Mechanism of the Inhibitory Effect of Progesterone on Lymphocyte Cytotoxicity: I. Progesterone‐Treated Lymphocytes Release a Substance Inhibiting Cytotoxicity and Prostaglandin Synthesis
Abstract
ABSTRACT:Progesterone‐treated lymphocytes (generator lymphocytes) of healthy pregnant women release a nondialyzable factor that inhibits both cytotoxic activity and prostaglandin F 2 α synthesis of test lymphocytes. Production of this factor is blocked by protein synthesis inhibitors (cycloheximide and actinomycin D). Sodium dodecylsulfate polyacrylamide electrophoresis of the partially purified material revealed a main 34,000 MW protein band. Progesterone‐treated lymphocytes of pregnant women showing clinical symptoms of threatened preterm delivery (risk group) failed to release this substance.
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Citations
Cited by
Actions of Placental and Fetal Adrenal Steroid Hormones in Primate Pregnancy*
PEPE, G. J., & ALBRECHT, E. D. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-5-608 · Cited by 498
Progesterone and the immunology of pregnancy
Druckmann, R., & Druckmann, M.-A. (2005) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2005.08.010 · Cited by 306
Cortisol and susceptibility to malaria during pregnancy
Bouyou-Akotet, M. K., Adegnika, A. A., Agnandji, S. T., Ngou-Milama, E., Kombila, M., Kremsner, P. G., & Mavoungou, E. (2005) · Microbes and Infection · doi:10.1016/j.micinf.2005.04.008 · Cited by 64
Metadata
- Authors
- SZEKERES‐BARTHO, J., KILAŔ, F., FALKAY, G., CSERNUS, V., TÖRÖK, A., & PACSA, A. S.
- Venue
- American Journal of Reproductive Immunology and Microbiology
- Publisher
- Wiley
- Published
- 1985-09
- Volume
- 9
- Issue
- 1
- Pages
- 15-18
- ISSN
- 0271-7352 (ISSN-L)
- 8755-8920
- OpenAlex
- W1527981787
- Cited by
- 165
- References
- 0
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Mechanism of the Inhibitory Effect of Progesterone on Lymphocyte Cytotoxicity: I. Progesterone‐Treated Lymphocytes Release a Substance Inhibiting Cytotoxicity and Prostaglandin Synthesis. https://app.cochat.ai/papers/10.1111/j.1600-0897.1985.tb00334.x
- The paper
- SZEKERES‐BARTHO, J., KILAŔ, F., FALKAY, G., CSERNUS, V., TÖRÖK, A., & PACSA, A. S. (1985). The Mechanism of the Inhibitory Effect of Progesterone on Lymphocyte Cytotoxicity: I. Progesterone‐Treated Lymphocytes Release a Substance Inhibiting Cytotoxicity and Prostaglandin Synthesis. American Journal of Reproductive Immunology and Microbiology. https://doi.org/10.1111/j.1600-0897.1985.tb00334.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
