The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Exercise Training After Lung Transplantation Improves Participation in Daily Activity: A Randomized Controlled Trial
Open accessAbstract
The effects of exercise training after lung transplantation have not been studied in a randomized controlled trial so far. We investigated whether 3 months of supervised training, initiated immediately after hospital discharge, improve functional recovery and cardiovascular morbidity of patients up to 1 year after lung transplantation. Patients older than 40 years, who experienced an uncomplicated postoperative period, were eligible for this single blind, parallel group study. Sealed envelopes were used to randomly allocate patients to 3 months of exercise training (n = 21) or a control intervention (n = 19). Minutes of daily walking time (primary outcome), physical fitness, quality of life and cardiovascular morbidity were compared between groups adjusting for baseline assessments in a mixed models analysis. After 1 year daily walking time in the treated patients (n = 18) was 85 ± 27 min and in the control group (n = 16) 54 ± 30 min (adjusted difference 26 min [95%CI 8-45 min, p = 0.006]). Quadriceps force (p = 0.001), 6-minute walking distance (p = 0.002) and self-reported physical functioning (p = 0.039) were significantly higher in the intervention group. Average 24 h ambulatory blood pressures were significantly lower in the treated patients (p ≤ 0.01). Based on these results patients should be strongly encouraged to participate in an exercise training intervention after lung transplantation.
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“Regular physical exercise has a positive effect on quality of life, exercise capacity and post-transplant hypertension in LTx patients[46,47] and we encourage all our patients to regularly perform exercises by themselves or to take part in medical training programs, depending on their capabilities.”
From Adherence is associated with a favorable outcome after lung transplantation (2019) · cites this paper as [47]
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Cites
Physical Activity and Public Health in Older Adults
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Characteristics of physical activities in daily life in chronic obstructive pulmonary disease
Pitta, F., Troosters, T., Spruit, M. A., Probst, V. S., Decramer, M., & Gosselink, R. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200407-855oc · Cited by 1,256
Self-citationChristie, J. D., Edwards, L. B., Kucheryavaya, A. Y., Aurora, P., Dobbels, F., Kirk, R., Rahmel, A. O., Stehlik, J., & Hertz, M. I. (2010) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2010.08.004 · Cited by 674
Randomization and allocation concealment: a practical guide for researchers
Doig, G. S., & Simpson, F. O. (2005) · Journal of Critical Care · doi:10.1016/j.jcrc.2005.04.005 · Cited by 664
Cornelissen, V. A., & Fagard, R. H. (2005) · Journal of Hypertension · doi:10.1097/00004872-200502000-00003 · Cited by 439
Interpretation of treatment changes in 6-minute walk distance in patients with COPD
Puhan, M. A., Mador, M. J., Held, U., Goldstein, R., Guyatt, G. H., & Schünemann, H. J. (2008) · European Respiratory Journal · doi:10.1183/09031936.00140507 · Cited by 373
Studer, S. M., Levy, R. D., McNeil, K., & Orens, J. B. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00065004 · Cited by 188
The Anti-Hypertensive Effects of Exercise
Hamer, M. (2006) · Sports Medicine · doi:10.2165/00007256-200636020-00002 · Cited by 168
Maury, G., Langer, D., Verleden, G. M., Dupont, L., Gosselink, R., Decramer, M., & Troosters, T. (2008) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2008.02209.x · Cited by 142
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Rochester, C. L., Vogiatzis, I., Holland, A. E., Lareau, S. C., Marciniuk, D. D., Puhan, M. A., Spruit, M. A., Masefield, S. C., Casaburi, R. H., Clini, E. M., et al. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201510-1966st · Cited by 908
Self-citationExercise as a prescription for patients with various diseases
Luan, X., Tian, X., Zhang, H., Huang, R., Li, N., Chen, P., & Wang, R. (2019) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2019.04.002 · Cited by 459
Dowman, L., McDonald, C. F., Hill, C. J., Lee, A. L., Barker, K., Boote, C., Glaspole, I., Goh, N. S. L., Southcott, A. M., Burge, A. T., et al. (2017) · Thorax · doi:10.1136/thoraxjnl-2016-208638 · Cited by 279
Report from the American Society of Transplantation on frailty in solid organ transplantation
KOBASHIGAWA, J. A., Dadhania, D. M., Bhorade, S. M., Adey, D., Berger, J., Bhat, G., Budev, M. M., Duarte‐Rojo, A., Dunn, M. A., HALL, S. A., et al. (2018) · American Journal of Transplantation · doi:10.1111/ajt.15198 · Cited by 241
Physiotherapy for cystic fibrosis in Australia and New Zealand: A clinical practice guideline
Button, B., Wilson, C. J., Dentice, R. L., Cox, N. S., Middleton, A., Tannenbaum, E., Bishop, J., Cobb, R., Burton, K., Wood, M., et al. (2016) · Respirology · doi:10.1111/resp.12764 · Cited by 151
Metadata
- Authors
- Langer, D., Burtin, C., Schepers, L., Ivanova, A., Verleden, G., Decramer, M., Troosters, T., & Gosselink, R.
- Affiliations
- KU Leuven (BE)
- Corresponding author
- Gosselink, R.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2012-06
- Volume
- 12
- Issue
- 6
- Pages
- 1584-1592
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W2131033885
- Cited by
- 170
- References
- 30
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 9 · 2023: 15 · 2022: 10 · 2021: 12 · 2020: 10 · 2019: 15 · 2018: 15 · 2017: 15 · 2016: 14 · 2015: 13 · 2014: 11 · 2013: 8 · 2012: 4
- FWCI
- 11.67
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- American Journal of Transplantation (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Lirias (submittedVersion, other-oa)
- Funders
- Fonds Wetenschappelijk Onderzoek
- Vlaamse regering
- Topics
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- lung transplantation, exercise training, supervised rehabilitation, functional recovery, physical fitness, cardiovascular morbidity, ambulatory blood pressure, quality of life, physical function, postoperative recovery
- MeSH terms
- Activities of Daily Living, Humans, Exercise, Lung Transplantation
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