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Surgical site infection – a European perspective of incidence and economic burden
Abstract
This retrospective review of reported surgical site infection (SSI) rates in Europe was undertaken to obtain an estimated scale of the problem and the associated economic burden. Preliminary literature searches revealed incomplete datasets when applying the National Nosocomial Infection Surveillance System criteria. Following an expanded literature search, studies were selected according to the number of parameters reported, from those identified as critical for accurate determination of SSI rates. Forty‐eight studies were analysed. None of the reviewed studies recorded all the data necessary to enable a comparative assessment of the SSI rate to be undertaken. The estimated range from selected studies analysed varied widely from 1·5–20% – a consequence of inconsistencies in data collection methods, surveillance criteria and wide variations in the surgical procedures investigated – often unspecified. SSIs contribute greatly to the economic costs of surgical procedures – estimated range: €1·47–19·1 billion. The analysis suggests that the true rate of SSIs, currently unknown, is likely to have been previously under‐reported. Consequently, the associated economic burden is also likely to be underestimated. A significant improvement in study design, data collection, analysis and reporting will be necessary to ensure that SSI baseline rates are more accurately assessed to enable the evaluation of future cost‐effective measures.
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“The existence of infection slows the healing process, induces chronic inflammation, and enhances the risk of systemic complications such as cellulitis, osteomyelitis, sepsis, and even mortality in extreme cases (Bowler et al. 2001; Leaper et al. 2004).”
From Nutritional Immunity in Wound Infection: Unveiling the Role of Dietary Elements in Host–Pathogen Interaction (2025) · cites this paper as Leaper et al. 2004
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Cited by
Sorted by citations
Surgical site infections: epidemiology, microbiology and prevention
Owens, C. D., & Stoessel, K. (2008) · Journal of Hospital Infection · doi:10.1016/s0195-6701(08)60017-1 · Cited by 987
Chen, C., Hu, X., He, D., He, X., & Shen, L. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70854 · Cited by 6
Metadata
- Authors
- Leaper, D. J., Van Goor, H., Reilly, J., Petrosillo, N., Geiss, H. K., Torres, A. J., & Berger, A.
- Venue
- International Wound Journal
- Publisher
- Wiley
- Published
- 2004-12
- Volume
- 1
- Issue
- 4
- Pages
- 247-273
- ISSN
- 1742-4801
- 1742-481X
- Cited by
- 240
- References
- 0
- Language
- en
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- Leaper, D. J., Van Goor, H., Reilly, J., Petrosillo, N., Geiss, H. K., Torres, A. J., & Berger, A. (2004). Surgical site infection – a European perspective of incidence and economic burden. International Wound Journal. https://doi.org/10.1111/j.1742-4801.2004.00067.x