The DOI matches its Crossref record; 240 of the 246 references it cites were found in a registry or an index.
Physiology of women's sexual function: basic knowledge and new findings.
Abstract
INTRODUCTION: Data concerning the physiology of female sexual functioning are still obtained from animal studies, but an increasing amount of novel evidence comes from human studies. AIM: To gain knowledge of psychological and biologic physiology of women's sexual functioning, mainly addressing sexual arousal and orgasm. METHODS: A broad-based literature review of current knowledge of the psychological and biologic physiology aspects of women's sexual functioning. RESULTS: A comprehensive understanding of the anatomical, neurobiological, and psychological mechanisms behind sexual function and responses is of paramount importance. A biopsychological paradigm was considered when reviewing currently available data, thus considering aspects of: (i) sexual differentiation of the brain, which is critical for sex differentiation in behavior; (ii) central neurobiology of sexual function, highlighting specific and innovative findings from neuroimaging methods that enable visualization of active brain areas during arousal and orgasm; and (iii) peripheral functional anatomy, mainly addressing genital arousal and orgasm. Translational science was also covered, providing data about the actual role of sexual arousal in women in both procreation/reproduction and recreation/pleasure. The interaction between physiological and psychological states of women's sexual response, nonspecific sexual response, interoceptive awareness, and flexibility of sexual interests have also been addressed. CONCLUSION: Further research on normal physiology of women's sexual function is needed in order to expand and "translate" current knowledge into the pathophysiological clinical setting. This manuscript encompasses data presented at the 3rd International Consultation on Sexual Medicine in Paris, France, July 10-13, 2009.
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“The degree of discordance between the subjective experience of arousal and the physiological response has been hypothesized as a function of interoceptive awareness or the ability to consciously register internal bodily sensations (9,10).”
From Effects of Mindfulness Training on Body Awareness to Sexual Stimuli: Implications for Female Sexual Dysfunction (2011) · cites this paper as [9]
Citations
Cites
Items 201–240 of 240
Dynamic MR Imaging of the Sexual Arousal Response in Women
Maravilla, K. A., Heiman, J. R., Garland, P. A., Cao, Y., CARTER, B. T., PETERSON, W. O., & Weisskoff, R. M. (2003) · Journal of Sex & Marital Therapy · doi:10.1080/713847132 · Cited by 36
Self-citationAssessment of sexual functioning during the menstrual cycle
Clayton, A. H., Clavet, G. J., McGarvey, E. L., Warnock, J. K., & Weiss, K. (1999) · Journal of Sex & Marital Therapy · doi:10.1080/00926239908404005 · Cited by 36
Everaerd, W. T. A. M., Laan, E. T. M., Both, S., & Spiering, M. (2001) · Data Archiving and Networked Services (DANS) · Cited by 35
Female sexual arousal: a behavioral analysis
Polan, M. L., Desmond, J. E., Banner, L. L., Pryor, M. R., McCallum, S. W., Atlas, S. W., Glover, G. H., & Arnow, B. A. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)02210-6 · Cited by 34
Effects of Mating on c-fos Expression in the Brains of Male Macaques
Michael, R. P., Clancy, A. N., & Zumpe, D. (1999) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00329-1 · Cited by 34
An Anal Probe for Monitoring Vascular and Muscular Events During Sexual Response
Bohlen, J. G., & Held, J. P. (1979) · Psychophysiology · doi:10.1111/j.1469-8986.1979.tb02998.x · Cited by 34
Intracavitary Circulation of Aqueous Material in the Human Vagina1
Odeblad, E. (1964) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016346409162686 · Cited by 33
Expression of Aquaporin Water Channels in Rat Vagina: Potential Role in Vaginal Lubrication
Park, K., Han, H. J., Kim, S. W., Jung, S. I., Kim, S., Lee, H.-S., Lee, M. N., & Ahn, K. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00650.x · Cited by 31
Simultaneous Measurement of Pelvic Floor Muscle Activity and Vaginal Blood Flow: A Pilot Study
Both, S., & Laan, E. T. M. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00457.x · Cited by 31
Peptidergic innervation of the human clitoris
Hauser‐Kronberger, C., Cheung, A., Hacker, G. W., Graf, A.-H., Dietze, O., & Frick, J. (1999) · Peptides · doi:10.1016/s0196-9781(99)00005-4 · Cited by 30
Histology and immunohistochemical studies of female genital tissue
Jannini, E. A., d’Amati, G., & Lenzi, A. (2005) · CRC Press eBooks · doi:10.1201/b14618-19 · Cited by 30
A comparison of structural patterns of sexual arousal in male and female homosexuals
Wincze, J. P., & Qualls, C. B. (1984) · Archives of Sexual Behavior · doi:10.1007/bf01541908 · Cited by 29
Quantitative evaluation of sensory nerve endings in hypertrophy of labia minora pudendi in women
Malinovský, L., Sommerová, J., & Martincík, J. (1975) · Cells Tissues Organs · doi:10.1159/000144435 · Cited by 24
Yang, C. C., Cao, Y. Y., Guan, Q., Heiman, J. R., Kuffel, S. W., Peterson, B. T., & Maravilla, K. R. (2007) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901625 · Cited by 23
Self-citationLevin, R. J. (1997) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1997.tb00050.x · Cited by 22
Self-citationAllers, K. A., Richards, N., Sultana, S. R., Sudworth, M., Dawkins, T. E., Hawcock, A. B., Buchanon, T., Casey, J. H., & Wayman, C. P. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01465.x · Cited by 21
Battaglia, C., Nappi, R. E., Sisti, G., Persico, N., Busacchi, P., & Venturoli, S. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01430.x · Cited by 21
Nitric Oxide-Cyclic GMP Signaling Pathway in the Regulation of Rabbit Clitoral Cavernosum Tone 1
Park, J. K., Kim, J. U., Lee, S. O., Hwang, P. H., Yi, H. K., Kim, Y. G., & Cho, K. W. (2002) · Experimental Biology and Medicine · doi:10.1177/153537020222701111 · Cited by 21
YILMAZ, U., SOYLU, A., Özcan, C., & Çalışkan, Ö. (2002) · The Journal of Urology · doi:10.1016/s0022-5347(01)69097-9 · Cited by 21
Meston, C. M., & McCall, K. (2005) · Journal of Sex & Marital Therapy · doi:10.1080/00926230590950217 · Cited by 19
Anatomy and Physiology of Women's Sexual Function
Graziottin, A., & Giraldi, A. G. E. (2006) · doi:10.1002/9780470755235.ch19 · Cited by 18
Self-citationThe involvement of the human cervix in reproduction and sex
Levin, R. J. (2005) · Sexual & Relationship Therapy · doi:10.1080/14681990500113195 · Cited by 18
Self-citationSerotonin receptor involvement in effects of restraint on female rat lordosis behavior
Uphouse, L. L., Hiegel, C., Perez, E. E., & Guptarak, J. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.02.007 · Cited by 17
4 Response of the Circumvaginal Musculature During Masturbation
Bohlen, J. G., Held, J. P., & Sanderson, M. O. (2015) · KARGER eBooks · doi:10.1159/000403076 · Cited by 14
Nugent, B. M., Wright, C. L., Zup, S., & McCarthy, M. (2008) · Physiology and Behavior · doi:10.1016/j.physbeh.2008.10.007 · Cited by 13
Self-citationLevin, R. J., & MacDonagh, R. (1993) · Archives of Sexual Behavior · doi:10.1007/bf01542560 · Cited by 13
Self-citationAllers, K. A., Richards, N., Scott, L., Sweatman, C., Cheung, J., Reynolds, D. S., Casey, J. H., & Wayman, C. P. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01466.x · Cited by 13
Vascular physiology of female sexual function
Giraldi, A. G. E., & Levin, R. J. (2005) · CRC Press eBooks · doi:10.1201/b14618-25 · Cited by 13
Self-citationChapter 7 The Neuroendocrine Control of Sex Specific Behavior in Vertebrates
McCarthy, M. M., & Ball, G. F. (2008) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)00407-9 · Cited by 12
Self-citationBattaglia, C., Nappi, R. E., Cianciosi, A., Busacchi, P., Sisti, G., Paradisi, R., & Venturoli, S. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2009.01402.x · Cited by 12
Creighton, S. M., Crouch, N. S., Foxwell, N., & Cellek, S. (2003) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901162 · Cited by 10
Human vaginal fluid-ionic composition and modification by sexual arousal [proceedings].
Rj, L., & Wagner, G. (1977) · PubMed · Cited by 10
Single case studies in human sexuality – important or idiosyncratic?
Levin, R. J. (2007) · Sexual & Relationship Therapy · doi:10.1080/14681990701633439 · Cited by 8
Self-citationMunarriz, R. M., Kim, N. N., TRAISH, A. M., & Goldstein, I. (2004) · Elsevier eBooks · doi:10.1016/b978-0-7234-3266-1.50025-5 · Cited by 8
Neurophysiology of female genital sexual response
Giuliano, F., & Julia-Guilloteau, V. (2005) · CRC Press eBooks · doi:10.1201/b14618-24 · Cited by 7
O’Connell, H. E., & Sanjeevan, K. V. (2005) · CRC Press eBooks · doi:10.1201/b14618-17 · Cited by 6
Innervation of the vagina and vulva
Hoyt, R. (2005) · CRC Press eBooks · doi:10.1201/b14618-18 · Cited by 6
Are normal hemodynamic responses invariably associated with normal penile rigidity and potency?
Erdoğru, T., Savaş, M., Yılmaz, N., & Baykara, M. (2001) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3900634 · Cited by 5
Anatomy of the pelvic floor and pelvic organ support system
Houten, T. V. (2005) · CRC Press eBooks · doi:10.1201/b14618-20 · Cited by 3
Research works printed but not linked: 13
- Pfaff, 2009, Cellular and molecular mechanisms of female reproductive behaviors, Physiology of reproduction: Female reproductive behavior, 107
- Fadul, 2005, Focal paraneoplastic limbic encephalitis presenting as orgasmic epilepsy, J Neurooncol, 72, 195, 10.1007/s11060-004-2242-9 · DOI
- Riley, 1983, Cholinergic and adrenergic control of human sexual responses, Psychopharmacology and sexual disorders, 125
- Riley, 1992, An ultrasound study of human coitus, Sex matters, 29
- Wagner, 1979, Vaginal transudation, The biology of the fluids in the female genital tract, 25
- Lee, 2009, Expression and localization of aquaporins in human vagina. 3rd International Consultation on Sexual Medicine, Le Palais de Congres, Paris Poster, 16, 1583
- Grafenberg, 1950, The role of urethra in the female orgasm, Int J Sexol, 3, 145
- Minh, 1981, Role du fascia de Halban dans la physiologie orgasmique feminime, Cahiers de Sexuol Clin, 7, 169
- Graziottin, 2006, Anatomy and physiology of women’s sexual function, Standard practice in sexual medicine, 289, 10.1002/9780470755235.ch19 · DOI
- Beck, 1974, How do the spermatozoa enter the uterus?, Am J Obstet Gynecol, 7, 350
- Geer, 1992, The information preocessing approach to human sexuality, The structure of emotion. Psychophysiological, cognitive and clinical aspects, 128
- Blackford, 1996, Differences in subjective arousal in heterosexual, bisexual and lesbian women, Can J Hum Sex, 5, 157
- Polan, 2003, Female sexual arousal: A behavioral analysis, Fertil Steril, 80, 1480, 10.1016/S0015-0282(03)02210-6 · DOI
Cited by
Sorted by citations
The human sexual response cycle: Brain imaging evidence linking sex to other pleasures
Georgiadis, J. R., & Kringelbach, M. L. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.05.004 · Cited by 421
Self-citationToward a More Evidence-Based Nosology and Nomenclature for Female Sexual Dysfunctions—Part II
Parish, S. J., Goldstein, A. T., Goldstein, S. W., Goldstein, I., Pfaus, J. G., Clayton, A. H., Giraldi, A. G. E., Simon, J. A., Althof, S. E., Bachmann, G. A., et al. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.09.020 · Cited by 193
Self-citation(2019) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000003324 · Cited by 174
Silverstein, R. G., Brown, A.-C. H., Roth, H. D., & Britton, W. B. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318234e628 · Cited by 168
“The degree of discordance between the subjective experience of arousal and the physiological response has been hypothesized as a function of interoceptive awareness or the ability to consciously register internal bodily sensations (9,10).”
BackgroundPuppo, V. (2012) · Clinical Anatomy · doi:10.1002/ca.22177 · Cited by 137
Metadata
- Authors
- Salonia, A., Giraldi, A., Chivers, M. L., Georgiadis, J. R., Levin, R., Maravilla, K. R., & McCarthy, M. M.
- Affiliations
- Vita-Salute San Raffaele University (IT)
- Rigshospitalet (DK)
- Queen's University (CA)
- University Medical Center Groningen (NL)
- Porter Brook Medical Centre (GB)
- University of Washington (US)
- University of Maryland, Baltimore (US)
- Corresponding author
- Salonia, Andrea
- ORCID
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-08-01
- Volume
- 7
- Issue
- 8
- Pages
- 2637-2660
- ISSN
- 1743-6095 (ISSN-L)
- 1743-6109
- OpenAlex
- W1678617888
- Cited by
- 132
- References
- 246
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 8 · 2023: 6 · 2022: 6 · 2021: 6 · 2020: 1 · 2019: 10 · 2018: 9 · 2017: 10 · 2016: 16 · 2015: 9 · 2014: 10 · 2013: 9 · 2012: 12
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- The Journal of Sexual Medicine (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Keywords
- female sexual function, sexual arousal, orgasm, sexual response cycle, sexual differentiation of the brain, genital anatomy, interoceptive awareness, sexual interest, female sexuality
- MeSH terms
- Animals, Brain, Cerebral Cortex, Female, Genitalia, Female, Humans, Libido, Magnetic Resonance Imaging, Nerve Net, Orgasm, Peripheral Nerves, Rodentia, Sexual Dysfunction, Physiological, Gonadal Steroid Hormones, Spinal Cord, Sexual Dysfunctions, Psychological, Positron-Emission Tomography
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