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Occurrence and Localization of Catechol Amines in the Human Brain
Abstract
B ertler Å.,Occurrence and localization of catechol amines in the human brain. The content of noradrenaline, dopamine and 5‐hydroxytryptamine (5‐HT) in various structures of the human brain has been investigated. Noradrenaline in rather high concentrations was found in the anterior and middle portion of the hypothalamus, and lower levels were recorded in structures of the mesencephalon and the floor of the 4th ventricle. Dopamine showed a very strict localization to structures which are involved in the extra‐pyramidal system, i. e. the basal ganglia and the substantia nigra suggesting that it may be involved in the function of this system. Relatively high concentrations of 5‐HT were found in the hypothalamus, the medulla oblongata, the corpus striatum and the thalamus.
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Cited by
Bernheimer, H., Birkmayer, W., Hornykiewicz, O., Jellinger, K., & Seitelberger, F. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90175-5 · Cited by 2,651
A Quantitative Study on the Nigro‐Neostriatal Dopamine Neuron System in the Rat
Andén, N., Fuxe, K., Hamberoer, B., & Hökfelt, T. (1966) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1966.tb03317.x · Cited by 379
Brown, R. M., Crane, A. M., & Goldman, P. S. (1979) · Brain Research · doi:10.1016/0006-8993(79)90132-x · Cited by 330
Serotonin in Parkinson's disease
Politis, M., & Niccolini, F. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.07.037 · Cited by 306
Kish, S. J., Shannak, K., Rajput, A., Deck, J. H. N., & Hornykiewicz, O. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb09766.x · Cited by 272
Metadata
- Authors
- Bertler, Å.
- Venue
- Acta Physiologica Scandinavica
- Publisher
- Wiley
- Published
- 1961-02
- Volume
- 51
- Issue
- 2-3
- Pages
- 97-107
- ISSN
- 0001-6772 (ISSN-L)
- 1365-201X
- OpenAlex
- W1982824019
- Cited by
- 242
- References
- 0
- FWCI
- 9.73
- Type
- journal article
- Language
- en
- Open access
- closed
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