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Cited by 269

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

EFFECTS OF ARTERIAL CARBON DIOXIDE TENSION AND OXYGEN SATURATION ON CEREBRAL BLOOD FLOW AUTOREGULATION IN DOGS

HÄGGENDAL, EGIL, JOHANSSON, BÖRJE·1965·Acta Physiologica Scandinavica

Abstract

Effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs. Acta physiol. scand. 1965. 66. Suppl. 258. 27–53. ‐ Pressure‐flow relation‐ ships of the cerebral circulation under influence of variations in arterial carbon dioxide tension and oxygen saturation were studied in pentobarbital anaesthetized dogs. Cerebral blood flow was measured by recording of the γ‐ emission of radioactive krypton (Kr 85), which was injected into the vertebral artery. The recorded desaturation curve was resolved into two exponential phases and the fast phase was considered as representative of blood flow in the grey matter of the brain. It was demonstrated that autoregulation of flow occurred within wide pressure limits under normo‐ and hypocapnia. Auto‐regulation was less pronounced under hypercapnia and was abolished at low arterial oxygen saturation. Possible mechanisms of autoregulation of cerebral blood flow are discussed. Evidences are presented which speak against the theory that changes in the carbon dioxide tension are the main cause of this autoregulation. The results from previous studies concerning the principal effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow were confirmed.

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Crossref · 10.1111/j.1748-1716.1965.tb03234.x

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Metadata

Authors
HÄGGENDAL, E., & JOHANSSON, B.
Venue
Acta Physiologica Scandinavica
Publisher
Wiley
Published
1965-02
Volume
66
Issue
s258
Pages
27-53
ISSN
  • 0001-6772 (ISSN-L)
  • 1365-201X
OpenAlex
W2151630875
Cited by
269
References
1
FWCI
14.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: EFFECTS OF ARTERIAL CARBON DIOXIDE TENSION AND OXYGEN SATURATION ON CEREBRAL BLOOD FLOW AUTOREGULATION IN DOGS. https://app.cochat.ai/papers/10.1111/j.1748-1716.1965.tb03234.x
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HÄGGENDAL, E., & JOHANSSON, B. (1965). EFFECTS OF ARTERIAL CARBON DIOXIDE TENSION AND OXYGEN SATURATION ON CEREBRAL BLOOD FLOW AUTOREGULATION IN DOGS. Acta Physiologica Scandinavica. https://doi.org/10.1111/j.1748-1716.1965.tb03234.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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