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Response to Submaximal and Maximal Exercise at Different Levels of Carboxyhemoglobin
Abstract
Five subjects performed submaximal and maximal bicycle and maximal treadmill exercise in normalcy and after carbon monoxide inhalation, giving different levels of carboxyhemoglobin (COHb) in the blood. During maximal treadmill exercise work time on a fixed work load and maximal oxygen uptake were decreased with increasing level of COHb (r = 0.79 and r = 0.85, respectively). Peak blood lactate concentration and pulmonary ventilation were unchanged. Highest measured heart rate was lower in parallell with the increased COHb level compared to control studies. During submaximal work heart rate was increased and oxygen uptake was unchanged at the various levels of COHb. At low submaximal work loads blood lactate concentrations and oxygen deficit was unchanged but increased as work load and COHb‐level increased.
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“Ekblom and Huot (1972) reported a 9% reduction in V ˙O2 max of smokers with a 7% elevation in HbCO.”
From Effects of Habitual Smoking on Cardiorespiratory Responses to Sub-maximal Exercise (2004) · cites this paper as Ekblom and Huot (1972)
In the citing paper
“This suggests that a portion of the 9% lower V ˙O2 max (L/min) in smokers in the present study can be attributed to CO binding with Hb and a reduction in oxygen carrying capacity.”
From Effects of Habitual Smoking on Cardiorespiratory Responses to Sub-maximal Exercise (2004) · cites this paper as Ekblom and Huot (1972)
In the citing paper
“CO has a half‐life of 4–5 h based on ventilation, and acute exposures that increase [COHb] up to 10%–15% are typically not associated with side effects (Foresti et al., 2008) even during near‐maximal exercise (Ekblom & Huot, 1972).”
From Effect of live‐high, train‐low strategy induced by chronic low‐dose carbon monoxide exposure on haematological parameters and performance in trained individuals (2026) · cites this paper as Ekblom & Huot, 1972
In the citing paper
“Likewise, hypoxia induced by CO inhalation inhibits O 2 utilization, and thus reduces the aerobic capacity (Nielsen 1971, Ekblom & Huot 1972, Vogel & Gleser 1972, Horvath et al. 1975, Morse et al. 2008).”
From Carbon monoxide exposure during exercise performance: muscle and cerebral oxygenation (2012) · cites this paper as Ekblom & Huot 1972
In the citing paper
“For application in elite endurance athletes, it should also be mentioned that the absolute training intensity, especially in high-intensity sessions, might be impaired by increased COHb concentrations (due to reductions in VO2max and time to exhaustion (Schmidt and Prommer, 2005; Ekblom and Huot, 1972; Hogan et al., 1990; Richardson et al., 2002) and increased heart rate, lactate concentration and”
From Low-dose carbon monoxide inhalation to increase total hemoglobin mass and endurance performance: scientific evidence and implications (2024) · cites this paper as Ekblom and Huot, 1972
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Research works printed but not linked: 15
- 10.1152/ajplegacy.1941.132.2.426 · DOI · Paper page
- 10.1111/j.1748-1716.1943.tb02828.x · DOI
- Astrand P.‐O., 1970, Textbook of Work Physiology
- 10.1080/00039896.1969.10665473 · DOI
- Cederlund C. A.HolmgrenandB.Håkansson Computerized calculations of the total amount of hemoglobin in the body using the alveolar CO‐method.Acta med. stand.1966.Suppl.472.253–260. · DOI
- Chiodi H., 1941, Respiratory and circulatory responses to acute carbon monoxide poisoning, Amer. J. Physiol., 134, 683, 10.1152/ajplegacy.1941.134.4.683 · DOI
- Karlsson J. Lactate and phosphagen concentrations in working muscle of man (thesis).Acta physiol. scand.1971.Suppl.358.
- Klausen K. B.Rasmussen H.Gjellerod H.MadsenandF.Petersen Circulation metabolism and ventilation during prolonged exposure to carbon monoxide and to high altitude.Scand. J. clin. Lab. Invest.1968.Suppl.103.26–38. · DOI
- Pirnay F., 1971, Muscular exercise during intoxication by carbon monoxide, J. appl. Physiol., 34, 573, 10.1152/jappl.1971.31.4.573 · DOI
- 10.1152/ajplegacy.1944.141.1.17 · DOI · Paper page
- Saltin B., 1968, Response to submaximal and maximal exercise after bed rest and after training, Circulation, 38
- 10.1111/j.1748-1716.1948.tb00540.x · DOI
- 10.1152/jappl.1966.21.5.1589 · DOI
- 10.1111/j.1748-1716.1949.tb00589.x · DOI
- Vogel J. A., 1971, Oxygen transportation during exercise with carbon monoxide exposure, Fed. Proc., 30
Cited by
Effects of Habitual Smoking on Cardiorespiratory Responses to Sub-maximal Exercise
Kobayashi, Y., Takeuchi, T., Hosoi, T., & Loeppky, J. A. (2004) · Journal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science · doi:10.2114/jpa.23.163 · Cited by 72
Carbon monoxide exposure during exercise performance: muscle and cerebral oxygenation
Keramidas, M. E., Kounalakis, S. N., Eiken, O., & Mekjavic, I. B. (2012) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02363.x · Cited by 19
Gatterer, H., Dünnwald, T., Woyke, S., Faulhaber, M., Schumacher, Y. O., & Schobersberger, W. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1490205 · Cited by 13
Villanova, S., Porcelli, S., Ekström, L., & Cardinale, D. A. (2026) · Experimental Physiology · doi:10.1113/ep093005 · Cited by 5
Metadata
- Authors
- Ekblom, B., & Huot, R.
- Venue
- Acta Physiologica Scandinavica
- Publisher
- Wiley
- Published
- 1972-12
- Volume
- 86
- Issue
- 4
- Pages
- 474-482
- ISSN
- 0001-6772
- 1365-201X
- Cited by
- 69
- References
- 0
- Language
- en
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- Ekblom, B., & Huot, R. (1972). Response to Submaximal and Maximal Exercise at Different Levels of Carboxyhemoglobin. Acta Physiologica Scandinavica. https://doi.org/10.1111/j.1748-1716.1972.tb05350.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
