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Overview: Purinergic Mechanisms
Abstract
An overview of the history of studies of the biological actions of extracellular ATP is presented. The basis of the subdivision of receptors for purines into P1-purinoceptors for adenosine and P2-purinoceptors for ATP and ADP are considered, as well as the recent proposal for subdivision of the ATP receptors into P2X-, P2Y-, P2Z-, and P2T- purinoceptor subtypes. These purinoceptor subtypes are discussed with respect to their transduction mechanisms, their distribution, and their physiological roles, including their roles in cotransmission and neuromodulation.
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Cited by
Oxidative metabolism deficiencies in brains of patients with Alzheimer's disease
Hoyer, S. (1996) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1996.tb05868.x · Cited by 88
Neary, J. T., & Norenberg, M. D. (1992) · Progress in Brain Research · doi:10.1016/s0079-6123(08)61746-x · Cited by 57
Age as Risk Factor for Sporadic Dementia of the Alzheimer Type?
HOYER, S. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb56833.x · Cited by 38
Metadata
- Authors
- BURNSTOCK, G.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 1990-12
- Volume
- 603
- Issue
- 1
- Pages
- 1-17
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2035971243
- Cited by
- 403
- References
- 0
- FWCI
- 15.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- BURNSTOCK, G. (1990). Overview: Purinergic Mechanisms. Annals of the New York Academy of Sciences. https://doi.org/10.1111/j.1749-6632.1990.tb37657.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
