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PHOTOINDUCED GENERATION OF HYDROGEN PEROXIDE AND HYDROXYL RADICALS IN MELANINS
Abstract
The hydrogen peroxide produced during photolysis of melanin pigments has been measured using an oxidase electrode. The photooxidation has been shown to occur via the superoxide intermediate. In the presence of superoxide dismutase the rate of photo‐induced production of hydrogen peroxide is increased, reflecting the ability of melanin to scavenge superoxide radicals. Evidence for metal‐ion dependent formation of hydroxyl radicals during photooxidation of melanin pigments was obtained using electron spin resonance‐spin trapping procedures. Superoxide dismutase increased the rate of formation of hydroxyl radicals in the system. Mechanisms of metal ion‐induced production of hydroxyl radicals during photolysis of melanin pigments are discussed.
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Cited by
The Protective Role of Melanin Against UV Damage in Human Skin †
Brenner, M., & Hearing, V. J. (2008) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2007.00226.x · Cited by 1,741
The physical and chemical properties of eumelanin
Meredith, P., & Sarna, T. (2006) · Pigment Cell Research · doi:10.1111/j.1600-0749.2006.00345.x · Cited by 1,033
Self-citationKollias, N., Sayre, R. M., Zeise, L., & Chedekel, M. R. (1991) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(91)80147-a · Cited by 482
Wondrak, G. T., Jacobson, M. K., & Jacobson, E. L. (2006) · Photochemical & Photobiological Sciences · doi:10.1039/b504573h · Cited by 411
Sarna, T. (1992) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(92)85027-r · Cited by 396
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Metadata
- Authors
- Korytowski, W., Pilas, B., Sarna, T., & Kalyanaraman, B.
- Venue
- Photochemistry and Photobiology
- Publisher
- Wiley
- Published
- 1987-02
- Volume
- 45
- Issue
- 2
- Pages
- 185-190
- ISSN
- 0031-8655 (ISSN-L)
- 1751-1097
- OpenAlex
- W2003503672
- Cited by
- 170
- References
- 0
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: PHOTOINDUCED GENERATION OF HYDROGEN PEROXIDE AND HYDROXYL RADICALS IN MELANINS. https://app.cochat.ai/papers/10.1111/j.1751-1097.1987.tb05362.x
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- Korytowski, W., Pilas, B., Sarna, T., & Kalyanaraman, B. (1987). PHOTOINDUCED GENERATION OF HYDROGEN PEROXIDE AND HYDROXYL RADICALS IN MELANINS. Photochemistry and Photobiology. https://doi.org/10.1111/j.1751-1097.1987.tb05362.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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