Characterization of Endogenous Protoporphyrin IX Induced by δ-Aminolevulinic Acid in Resting and Activated Peripheral Blood Lymphocytes by Four-Color Flow Cytometry
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PpIX is preferentially accumulated only in activated T cells but not resting T cells without activation after ALA incubation, resulting in the selective killing of activated T cells by PDT.
“This is because PpIX is preferentially accumulated only in activated T cells but not resting T cells without activation after ALA incubation, resulting in the selective killing of activated T cells by PDT [159,160].”
From 5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy (2023) · cites this paper as [160]
ALA-PDT is able to selectively kill activated T cells including CD4 and CD8 cells.
“It is worth noting that ALA-PDT is able to selectively kill activated T cells including CD4 and CD8 cells.”
From 5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy (2023) · cites this paper as [160]
Cites
Photodynamic therapy with endogenous protoporphyrin
Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(90)85083-9 · Cited by 1,509 · see citing works
Berg, K., Anholt, H., Bech, Ø., & Moan, J. (1996) · British Journal of Cancer · doi:10.1038/bjc.1996.423 · Cited by 142 · see citing works
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5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
Howley, R., Chandratre, S., & Chen, B. (2023) · Bioengineering · doi:10.3390/bioengineering10040496 · Cited by 33 · see citing works
Darvekar, S., Juzenas, P., Oksvold, M., Kleinauskas, A., Holien, T., Christensen, E., Stokke, T., Sioud, M., & Peng, Q. (2020) · Cancers · doi:10.3390/cancers12020377 · Cited by 16 · see citing works
- Authors
- Hryhorenko, E. A., Rittenhouse-Diakun, K., Harvey, N. S., Morgan, J., Stewart, C. C., & Oseroff, A. R.
- ORCID
- Morgan, Janet
- Venue
- Photochemistry and Photobiology
- Publisher
- Wiley
- Published
- 1998-05
- Volume
- 67
- Issue
- 5
- Pages
- 565-572
- ISSN
- 0031-8655 (ISSN-L)
- 1751-1097
- OpenAlex
- W4254257437
- Cited by
- 31
- References
- 2
- Citations by year
- 2023: 1 · 2020: 4 · 2019: 1 · 2018: 1 · 2016: 1 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 4.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Photochemistry and Photobiology (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Porphyrin Metabolism and Disorders
- Physical Sciences › Materials Science › Materials Chemistry › Porphyrin and Phthalocyanine Chemistry
- Keywords
- protoporphyrin IX, 5-aminolevulinic acid, lymphocytes, lymphocyte activation, peripheral blood lymphocytes, porphyrin fluorescence, photosensitizers
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