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The quantitative measurement of motor inco-ordination in naive mice using an accelerating rotarod
Abstract
A simple modification of the standard rotarod apparatus is described which eliminates the necessity of time-consuming training and consequently gives a truer measure of motor co-ordination since any effects on memory are avoided. The sensitivity and reproducibility of the procedure are much greater than those obtained with constant speed rotarods and less animals are required to obtain statistically significant results.
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Cited by
Rogers, D. C., Fisher, E. M. C., Brown, S. D. M., Peters, J., Hunter, A. J., & Martin, J. E. (1997) · Mammalian Genome · doi:10.1007/s003359900551 · Cited by 795
Tests to assess motor phenotype in mice: a user's guide
Brooks, S. P., & Dunnett, S. B. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2652 · Cited by 621
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean
Clapham, J. C., Arch, J. R. S., Chapman, H., Haynes, A., Lister, C., Moore, G. B. T., Piercy, V., Carter, S. A., Lehner, I., Smith, S. A., et al. (2000) · Nature · doi:10.1038/35019082 · Cited by 604
A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel
Polomano, R. C., Mannes, A. J., Clark, U. S., & Bennett, G. J. (2001) · Pain · doi:10.1016/s0304-3959(01)00363-3 · Cited by 476
Pascual, M., Blanco, A. M., Cauli, O., Miñarro, J., & Guerri, C. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05298.x · Cited by 385
Metadata
- Authors
- Jones, B. J., & Roberts, D. J.
- Venue
- Journal of Pharmacy and Pharmacology
- Publisher
- Oxford University Press (OUP)
- Published
- 1968-04-01
- Volume
- 20
- Issue
- 4
- Pages
- 302-304
- ISSN
- 0022-3573 (ISSN-L)
- 2042-7158
- OpenAlex
- W1998290119
- Cited by
- 583
- References
- 0
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jones, B. J., & Roberts, D. J. (1968). The quantitative measurement of motor inco-ordination in naive mice using an accelerating rotarod. Journal of Pharmacy and Pharmacology. https://doi.org/10.1111/j.2042-7158.1968.tb09743.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
