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Cited by 23Dental Implant Techniques and OutcomesPeriodontal Regeneration and TreatmentsDental materials and restorations

Outcome measures and methods of assessment of soft tissue augmentation interventions in the context of dental implant therapy: A systematic review of clinical studies published in the last 10 years

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Avila‐Ortiz, Gustavo, Couso‐Queiruga, Emilio, Pirc, Miha, Chambrone, Leandro, Thoma, Daniel S.·2023·Journal of Clinical Periodontology
DOI 10.1111/jcpe.13597
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Abstract

Aim: To identify and report outcome measures and methods of assessment on soft tissue augmentation interventions in the context of dental implant therapy reported in clinical studies published in the last 10 years. Materials and Methods: The protocol of this Preferred Reporting Items of Systematic Reviews and Meta‐Analyses (PRISMA) 2020‐compliant systematic review was registered in PROSPERO (CRD42021252214). A literature search was conducted to identify articles that met the pre‐established eligibility criteria. Data of interest, with an emphasis on outcome measures, were extracted. For each outcome, specific methods and timing of assessment were described in detail. Following a critical qualitative analysis of the data, outcome measures were categorized. Primary outcomes were identified, and the frequency of reporting in the selected articles was calculated. Additionally, risk‐of‐bias assessments were performed for individual articles and primary outcomes. Results: Ninety‐two articles, of which 39 reported randomized controlled trials (RCTs), 20 non‐RCTs, and 33 case series studies, were selected. Outcome measures were categorized into either investigator‐evaluated outcome measures (i.e., clinical, digital imaging, aesthetic, histological, biomarker, and safety) or patient‐reported outcome measures (PROMs). Clinical outcomes were the most frequently reported type of outcome. Considering all categories, the most frequently reported primary outcomes were facial mucosa thickness assessed with clinical methods (22.83%), facial keratinized mucosa width assessed with clinical methods (19.57%), facial mucosal margin position/recession assessed with clinical methods (18.48%), facial mucosa thickness assessed with digital imaging methods (11.96%), facial soft tissue volume assessed with digital imaging methods (9.78%), and supracrestal tissue height assessed with clinical methods (9.78%). No distinguishable patterns of association between specific types or quality (level of bias) of clinical studies and the choice of primary outcomes were observed. Conclusions: Clinical research on peri‐implant soft tissue augmentation has progressively increased in the last 10 years. Although clinical outcome measures were the most frequently reported outcomes in the selected literature, trends in the field are indicative of a shift from traditional clinical assessment methods to the use of digital technologies. PROMs were generally under‐reported but should be considered an integral methodological component in future clinical studies.

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Cited by

Sorted by citations

Authors
Avila‐Ortiz, G., Couso‐Queiruga, E., Pirc, M., Chambrone, L., & Thoma, D. S.
Affiliations
  • Department of Periodontics University of Iowa College of Dentistry Iowa City Iowa USA
  • University of Iowa (US)
  • University of Zurich (CH)
ORCID
Venue
Journal of Clinical Periodontology
Publisher
Wiley
Published
2022-07-11
Volume
50
Issue
S25
Pages
83-95
ISSN
  • 0303-6979 (ISSN-L)
  • 1600-051X
DOI
10.1111/jcpe.13597
OpenAlex
W4210286225
Cited by
23
References
1
Citations by year
2026: 2 · 2025: 6 · 2024: 1 · 2023: 10 · 2022: 4
FWCI
1.02
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal Of Clinical Periodontology (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by-nc-nd)
  • BORIS (University Library Bern) (submittedVersion, cc-by-nc-nd)
  • Bern Open Repository and Information System (University of Bern) (submittedVersion, cc-by-nc)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc)
  • Zurich Open Repository and Archive (University of Zurich)
Topics
  • Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
  • Health Sciences › Medicine › Urology › Periodontal Regeneration and Treatments
  • Health Sciences › Dentistry › Orthodontics › Dental materials and restorations
Keywords
soft tissue augmentation, dental implants, peri-implant soft tissue, outcome measures, patient-reported outcome measures, keratinized mucosa width, digital imaging, soft tissue recession, histological outcomes, biomarkers, safety outcomes
MeSH terms
Dental Implantation, Esthetics, Dental, Humans, Mucous Membrane, Dental Implants, Outcome Assessment, Health Care

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